Combining neurologic and blood pressure drugs reduces breast tumor development in mice

Adding a medication used to treat epilepsy, bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high fat diet fed to their mothers during pregnancy. Conversely, this treatment combination increased breast cancer development in the offspring whose mothers had not been fed a high fat diet during pregnancy.

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AI improves breast cancer risk prediction

A sophisticated type of artificial intelligence (AI) can outperform existing models at predicting which women are at future risk of breast cancer, according to a new study.

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Large study links sustained weight loss to reduced breast cancer risk

A large new study finds that women who lost weight after age 50 and kept it off had a lower risk of breast cancer than women whose weight remained stable, helping answer a vexing question in cancer prevention.

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Origins of neurodegenerative disease

New research has shed light on the origins of spinocerebellar ataxia type 7 (SCA7) and demonstrates effective new therapeutic pathways for SCA7 and the more than 40 other types of spinocerebellar ataxia.

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Rectal microbes influence effectiveness of HIV vaccine

Microbes living in the rectum could make a difference to the effectiveness of experimental HIV vaccines, according to researchers.

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Bone bandage soaks up pro-healing biochemical to accelerate repair

Researchers have engineered a patch or bandage that captures a pro-healing molecule called adenosine that briefly surges at the site of a bone break or fracture to accelerate and improve the natural healing process. In a proof-of-principle study with mice, the bandage helped to accelerate callus formation and vascularization to achieve better bone repair by three weeks.

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Breast cancer cells swallow a 'free lunch' of dietary fat particles from the bloodstream

A research team has previously shown that fatty particles from the bloodstream may boost the growth of breast cancer cells. They now show that through an unexpected mechanism not previously described in cancer cells, the fat particles bind to the breast cancer cell surface and are then taken into the cell, providing a large supply of fuel that drives proliferation of the cancer cells.

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Efforts to end the HIV epidemic must not ignore people already living with HIV

Efforts to prevent new HIV transmissions in the US must be accompanied by addressing HIV-associated comorbidities to improve the health of people already living with HIV, experts assert.

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Lighting up cardiovascular problems using nanoparticles

A new nanoparticle innovation that detects unstable calcifications that can trigger heart attacks and strokes may allow doctors to pinpoint when plaque on the walls of blood vessels becomes dangerous.

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Long-term study finds faster breast cancer radiation treatment as effective as long course

Approximately half of the patients were randomly assigned whole breast radiation, delivered once per day over 3 to 5 weeks. The other half received external beam APBI which was given twice a day over 5 to 8 days. The study was long-term, with a median followup of 8.6 years.

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