Common osteoporosis drugs linked to 24% lower dementia risk in major study

A massive study of more than 120,000 older adults suggests that common osteoporosis drugs may reduce the risk of Alzheimer’s disease and other dementias by up to 24%. The surprising findings raise the possibility that medications already used to strengthen bones could also help protect the aging brain.

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Scientists wipe out deadly brain tumors in every mouse tested with new cancer therapy

Scientists at UC San Francisco have developed a powerful new cancer therapy that remains inactive until it reaches the brain, where it switches on to attack deadly tumors. The engineered immune cells, called B-SYNC CAR-T cells, completely eliminated diffuse midline glioma (DMG), an aggressive childhood brain cancer that is almost always fatal within a year, in two mouse models.

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Stronger flu shot linked to nearly 55% lower Alzheimer's risk

A surprising new study suggests that a stronger flu shot could offer older adults significantly greater protection against Alzheimer's disease. Researchers at UTHealth Houston analyzed nearly 200,000 adults ages 65 and older and found that those who received a high-dose influenza vaccine had a nearly 55% lower risk of developing Alzheimer's, compared with a 40% reduction previously associated with the standard-dose vaccine.

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Low testosterone linked to 18% higher risk of dying from cancer

A major international study tracking more than 26,000 men found that very low testosterone levels were associated with an 18% higher risk of dying from cancer later in life. Surprisingly, testosterone itself showed no clear link to prostate cancer, although two other sex hormones did. Researchers believe low testosterone could be an important early warning sign of future health risks, particularly when levels fall below 8.6 nmol/L.

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Scientists solve 30-year-old mystery and discover a hidden defense against inflammation

Scientists have solved a decades-old mystery and uncovered a hidden immune system defense that protects healthy cells from the very inflammation meant to fight infections. The surprising discovery could lead to new approaches for treating cancer, inflammatory bowel disease, and other conditions involving excessive inflammation.

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Scientists use sound waves to deliver a new attack on deadly brain cancer

Scientists at the University of Virginia have developed a promising new strategy to fight glioblastoma, one of the deadliest and most difficult-to-treat forms of brain cancer. Their experimental approach combines focused ultrasound, tiny nanoparticles, and genetic molecules called microRNAs to attack multiple cancer-driving genes simultaneously.

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Why some “lower-risk” childhood cancers turn deadly

Scientists have uncovered hidden aggressive cancer cells in children whose tumors were previously considered lower risk, revealing why some cases of rhabdomyosarcoma become unexpectedly deadly. The discovery could help doctors identify dangerous tumors earlier and develop personalized treatments that improve survival while reducing unnecessary chemotherapy.

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Low testosterone may make sugar far more harmful to your liver

Scientists have discovered that low testosterone and a high-fructose diet can work together to worsen fatty liver disease in mice. Unexpectedly, changes in gut bacteria appear to drive this harmful interaction, revealing a potential new target for preventing liver damage.

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Scientists discover how pancreatic cancer rewrites its DNA to escape treatment

Scientists have discovered how pancreatic cancer cells continually reshape their genetic makeup to become more aggressive, spread, and evade treatment. In laboratory experiments, blocking a key gene reversed some of these dangerous changes, revealing a potential new way to fight the deadly disease.

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Glioblastoma breakthrough reveals how brain cancer cells become more aggressive

Scientists discovered that the thick, sticky fluid surrounding glioblastoma tumors can make brain cancer cells smaller, more flexible, and better at invading surrounding tissue. Even more troubling, some of these changes persist after the cells leave the thick fluid, revealing a previously overlooked mechanism that could help this deadly cancer spread.

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