Cancer may be breaking its own DNA to keep growing

Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes with small mistakes that allow new mutations to accumulate. Researchers believe this self-inflicted damage may help tumors evolve while also creating a potential target for new treatments.

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Can’t sleep in the heat? These 8 tricks could save your night

Sleeping well during a heatwave starts with stopping the home from overheating. Close blinds against strong sunlight, ventilate when the air outside becomes cooler, and avoid using heat-producing appliances during the hottest hours. Moving to a cooler room, choosing light bedding and using fans or ice packs safely can also make hot nights more manageable.

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Why the same DNA damage causes cancer in some people but not others

A controlled mouse study has provided direct evidence that inherited genetics can steer how cancer begins and evolves after DNA damage. The discovery could eventually help doctors better predict cancer risk and tailor screening and treatments to each patient.

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CRISPR makes prostate cancer vulnerable to immunotherapy

Scientists used CRISPR to make prostate cancer cells easier for the immune system to detect and destroy. The experimental treatment dramatically improved the effects of immunotherapy in mice and may offer hope for other hard-to-treat tumors.

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New cancer strategy could stop tumors before resistance takes hold

Researchers are applying evolutionary theory to cancer by changing treatments before tumors have time to develop resistance. Mathematical models suggest that rapid, carefully timed switches between multiple therapies could improve cure rates.

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Heavy marijuana smoking may increase cancer risk, researchers warn

Heavy marijuana smoking may raise the risk of lung cancer and several head and neck cancers, according to growing research, but many important questions remain unanswered. Scientists are still trying to determine how much marijuana use is enough to significantly increase cancer risk. Edibles have not been linked to lung cancer so far, while the long-term effects of vaping marijuana and secondhand marijuana smoke are still being investigated.

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This frog bacterium wiped out cancer tumors in mice with a single dose

A naturally occurring bacterium from amphibian intestines completely eliminated colorectal tumors in mice with a single treatment by both attacking cancer cells and activating the immune system. The findings point to a promising new type of cancer therapy that could one day work against many solid tumors.

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A hidden immune backup system could supercharge mRNA cancer vaccines

Researchers found that mRNA cancer vaccines can recruit an unexpected immune cell to launch powerful tumor-fighting responses, overturning a long-held assumption about how the vaccines work. The discovery could lead to more effective cancer vaccines and help scientists tailor treatments for better patient outcomes.

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Tiny silica particles wiped out aggressive prostate cancer in mice

Tiny silica nanoparticles engineered to seek out prostate cancer caused tumor cells to self-destruct and supercharged the immune system in preclinical mouse studies. Combined with immunotherapy, the treatment produced complete remissions in multiple mice, raising hopes for a powerful new approach to prostate cancer.

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Creatine doesn't just build muscle. It may also help fight cancer

Scientists have discovered that creatine may strengthen one of the immune system's most important cancer-fighting pathways by energizing dendritic cells that activate killer T cells. The promising results could eventually help make immunotherapy more effective, but they have not yet been tested in human patients.

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