Breaking down AGEs: Insight into how lifestyle drives ER-positive breast cancer

Consumption of processed foods high in sugar and fat increase levels of advanced glycation end products (AGEs). Researchers report that AGE levels are higher in patients with estrogen receptor (ER)-positive than ER-negative breast cancer. Addition of AGEs caused breast cancer cells, whose growth had previously been controlled by tamoxifen, to begin to grow again. This suggests that patients with high AGEs may be less likely to respond to tamoxifen treatment.

from Women's Health News -- ScienceDaily http://bit.ly/2VjkXIj

Breaking down AGEs: Insight into how lifestyle drives ER-positive breast cancer

Consumption of processed foods high in sugar and fat increase levels of advanced glycation end products (AGEs). Researchers report that AGE levels are higher in patients with estrogen receptor (ER)-positive than ER-negative breast cancer. Addition of AGEs caused breast cancer cells, whose growth had previously been controlled by tamoxifen, to begin to grow again. This suggests that patients with high AGEs may be less likely to respond to tamoxifen treatment.

from Women's Health News -- ScienceDaily http://bit.ly/2VjkXIj

Breaking down AGEs: Insight into how lifestyle drives ER-positive breast cancer

Consumption of processed foods high in sugar and fat increase levels of advanced glycation end products (AGEs). Researchers report that AGE levels are higher in patients with estrogen receptor (ER)-positive than ER-negative breast cancer. Addition of AGEs caused breast cancer cells, whose growth had previously been controlled by tamoxifen, to begin to grow again. This suggests that patients with high AGEs may be less likely to respond to tamoxifen treatment.

from Breast Cancer News -- ScienceDaily http://bit.ly/2VjkXIj

Breast cancer drugs could help treat resistant lung cancers

A class of drugs used to treat certain breast cancers could help to tackle lung cancers that have become resistant to targeted therapies, a new study suggests. The research found that lung tumors in mice caused by mutations in a gene called EGFR shrunk significantly when a certain protein was blocked.

from Breast Cancer News -- ScienceDaily http://bit.ly/2RhCVvA

Confronting the side effects of a common anti-cancer treatment

Results of a new study suggest that a new treatment approach is needed -- and how this may be possible -- to address adverse effects of aromatase inhibitors, drugs commonly prescribed to both men and women to prevent recurrence of estrogen-positive breast cancer.

from Women's Health News -- ScienceDaily http://bit.ly/2AiN4OA

Confronting the side effects of a common anti-cancer treatment

Results of a new study suggest that a new treatment approach is needed -- and how this may be possible -- to address adverse effects of aromatase inhibitors, drugs commonly prescribed to both men and women to prevent recurrence of estrogen-positive breast cancer.

from Women's Health News -- ScienceDaily http://bit.ly/2AiN4OA

A novel mechanism that regulates cellular injury by phagocytes during inflammation

Phagocytes such as macrophages and neutrophils contain multiple lysosomes, which possess a variety of digestive enzymes. Upon stimulation, phagocytes secrete these digestive enzymes through a process called lysosomal exocytosis to lyse external pathogens or tumor cells. A research team has identified myoferlin as a critical regulator of this process. Furthermore, they found that it plays an important role in inducing cellular injury by phagocytes during inflammation.

from Women's Health News -- ScienceDaily http://bit.ly/2Si7Vss

A novel mechanism that regulates cellular injury by phagocytes during inflammation

Phagocytes such as macrophages and neutrophils contain multiple lysosomes, which possess a variety of digestive enzymes. Upon stimulation, phagocytes secrete these digestive enzymes through a process called lysosomal exocytosis to lyse external pathogens or tumor cells. A research team has identified myoferlin as a critical regulator of this process. Furthermore, they found that it plays an important role in inducing cellular injury by phagocytes during inflammation.

from Women's Health News -- ScienceDaily http://bit.ly/2Si7Vss

Delivery method associated with pelvic floor disorders after childbirth

Research has demonstrated that vaginal childbirth substantially increases the probability a woman will develop a pelvic floor disorder later in life.

from Women's Health News -- ScienceDaily https://ift.tt/2QDP7ai

Delivery method associated with pelvic floor disorders after childbirth

Research has demonstrated that vaginal childbirth substantially increases the probability a woman will develop a pelvic floor disorder later in life.

from Women's Health News -- ScienceDaily https://ift.tt/2QDP7ai