Disruption of a single amino acid in a cellular protein makes breast cancer cells behave like stem cells

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long noncoding RNA (lncRNA) 'XIST' could be an effective therapeutic strategy for treating aggressive breast cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/d9T0aZA

Breast cancers broadly defined by their genome architecture

Breast cancers at all stages are defined by the structure of their genomes, researchers find. Targeting these processes early is likely to offer unexpected therapeutic avenues.

from Women's Health News -- ScienceDaily visit

Breast cancers broadly defined by their genome architecture

Breast cancers at all stages are defined by the structure of their genomes, researchers find. Targeting these processes early is likely to offer unexpected therapeutic avenues.

from Breast Cancer News -- ScienceDaily https://ift.tt/U4wnRoy

Drug may counteract muscle loss and osteoporosis after rapid weight loss

Rapid weight loss affects muscle mass and can increase the risk of osteoporosis. But now there is good news for people taking weight loss medication who may be at risk. A new study indicates that the drug bimagrumab can counteract the side effects.

from Women's Health News -- ScienceDaily https://ift.tt/gvlUcxW

From muscle to memory: New research uses clues from the body to understand signaling in the brain

New research shows that a network of subcellular structures similar to those responsible for propagating molecular signals that make muscles contract are also responsible for transmitting signals in the brain that may facilitate learning and memory.

from Women's Health News -- ScienceDaily https://ift.tt/K062oVt

Fear of breast cancer recurrence: Impact and coping with being in a dark place

A new study of breast cancer survivors has found this psychosocial challenge impacts almost every important domain of their lives -- the emotional, behavioral, cognitive, relational and professional. A larger number of domains was affected, and they were affected more frequently in those with greater fear of recurrence. The majority of study participants indicated that they sought senses of purpose, belonging, control and connection with others.

from Breast Cancer News -- ScienceDaily https://ift.tt/cl4VxNq

Later-onset menopause linked to healthier blood vessels, lower heart disease risk

New research shows that women who hit menopause later in life have healthier blood vessels and mitochondria and a different composition of metabolites in their blood than those who stop menstruating earlier. The study helps explain why late-onset menopause is linked to lower risk of heart attacks and strokes.

from Women's Health News -- ScienceDaily https://ift.tt/FV3RpNy

Communication between body muscle and the brain influences fertility

A newly discovered line of communication between body muscle and the pituitary gland may play an unexpected role in female fertility, according to a new study. Researchers found that a protein produced in the muscles helps manage the release of a hormone made in the pea-sized gland attached to the base of the brain.

from Women's Health News -- ScienceDaily https://ift.tt/DvXxK79

How hungry fat cells could someday starve cancer to death

Liposuction and plastic surgery aren't often mentioned in the same breath as cancer. But they are the inspiration for a new approach to treating cancer that uses engineered fat cells to deprive tumors of nutrition. Researchers at UC San Francisco used the gene editing technology CRISPR to turn ordinary white fat cells into 'beige' fat cells, which voraciously consume calories to make heat.

from Breast Cancer News -- ScienceDaily https://ift.tt/WXIR60a

Inhibitor drugs to treat aggressive breast cancer identified

A national study seeking more effective treatment for deadly metaplastic breast cancer has identified two inhibitor drugs with the potential to interrupt disease progression.

from Breast Cancer News -- ScienceDaily https://ift.tt/z3SJk9w