Disruption of a single amino acid in a cellular protein makes breast cancer cells behave like stem cells

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long noncoding RNA (lncRNA) 'XIST' could be an effective therapeutic strategy for treating aggressive breast cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/d9T0aZA