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Friday, August 27, 2021

No swimming? Molecule regulating sperm motility discovered

Researchers used protein sequence data analysis and genome editing technology to find that sperm protein SPATA33 plays an important role in sperm motility regulation. Their findings will aid in the development of male contraceptives and the investigation of the cause of male infertility.

from Women's Health News -- ScienceDaily https://ift.tt/3sU1Sh1

Tuesday, August 24, 2021

High cholesterol fuels cancer by fostering resistance to a form of cell death

A research team has identified how breast cancer cells use cholesterol to develop tolerance to stress, making them impervious to death as they migrate from the original tumor site.

from Women's Health News -- ScienceDaily https://ift.tt/3guK4DW

High cholesterol fuels cancer by fostering resistance to a form of cell death

A research team has identified how breast cancer cells use cholesterol to develop tolerance to stress, making them impervious to death as they migrate from the original tumor site.

from Breast Cancer News -- ScienceDaily https://ift.tt/3guK4DW

High cholesterol fuels cancer by fostering resistance to a form of cell death

A research team has identified how breast cancer cells use cholesterol to develop tolerance to stress, making them impervious to death as they migrate from the original tumor site.

from Women's Health News -- ScienceDaily https://ift.tt/3guK4DW

Wednesday, August 18, 2021

Prediction models may reduce false-positives in MRI breast cancer screening

Prediction models based on clinical characteristics and imaging findings may help reduce the false-positive rate in women with dense breasts who undergo supplemental breast cancer screening with MRI, according to a new study.

from Breast Cancer News -- ScienceDaily https://ift.tt/2W7hb9R

Mechanisms of resistance to drug for triple-negative breast cancer identified

Triple-negative breast cancer cells exposed to the antibody-drug conjugate sacituzumab govitecan may develop resistance to this powerful drug through alterations in both the target of the antibody and the target of the toxic payload. The findings illustrate how uncovering such mechanisms will critically inform strategies to overcome resistance to sacituzumab govitecan.

from Breast Cancer News -- ScienceDaily https://ift.tt/3mg7DE7

Prediction models may reduce false-positives in MRI breast cancer screening

Prediction models based on clinical characteristics and imaging findings may help reduce the false-positive rate in women with dense breasts who undergo supplemental breast cancer screening with MRI, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/2W7hb9R

Mechanisms of resistance to drug for triple-negative breast cancer identified

Triple-negative breast cancer cells exposed to the antibody-drug conjugate sacituzumab govitecan may develop resistance to this powerful drug through alterations in both the target of the antibody and the target of the toxic payload. The findings illustrate how uncovering such mechanisms will critically inform strategies to overcome resistance to sacituzumab govitecan.

from Women's Health News -- ScienceDaily https://ift.tt/3mg7DE7

Prediction models may reduce false-positives in MRI breast cancer screening

Prediction models based on clinical characteristics and imaging findings may help reduce the false-positive rate in women with dense breasts who undergo supplemental breast cancer screening with MRI, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/2W7hb9R

Mechanisms of resistance to drug for triple-negative breast cancer identified

Triple-negative breast cancer cells exposed to the antibody-drug conjugate sacituzumab govitecan may develop resistance to this powerful drug through alterations in both the target of the antibody and the target of the toxic payload. The findings illustrate how uncovering such mechanisms will critically inform strategies to overcome resistance to sacituzumab govitecan.

from Women's Health News -- ScienceDaily https://ift.tt/3mg7DE7