How an egg cell's 'operating manual' sets the stage for fertility

Scientists have revealed in unprecedented detail the genetic instructions immature egg cells go through step by step as they mature into functionality. Their findings improve our understanding of how ovaries maintain a female's fertility.

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Light stimulation makes bones heavier

Researchers showed that laser ablation of bone inhibits expression of the osteogenesis inhibitor protein sclerostin without causing inflammation, unlike the conventional bur-drilling technique. Further investigations confirmed that this beneficial bio-stimulation works by inducing mechanical stress. These findings help advance research into the treatment of osteoporosis as well as specific enhancement of bone regrowth in orthopedic and dental surgery.

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Pregnancy complications linked to heightened risk of heart disease and stroke in later life

Pregnancy complications such as miscarriage, pre-eclampsia, diabetes in pregnancy (gestational diabetes) and pre-term birth are linked to a heightened risk of heart disease in later life, suggests an overarching (umbrella) analysis of data.

from Women's Health News -- ScienceDaily https://ift.tt/3nFbJ7k

New analytical model detects mutations in breast cancer

Researchers have developed a computational model which is effective in detecting and identifying genetic mutations in breast tumors. The study, the largest of its kind in the world, includes results from over 3,200 patients with breast cancer.

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Regulatory T cells could lead to new immunotherapies aimed at treating multiple sclerosis

Researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).

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Blood vessel growth in muscle is reduced in women after menopause

A new study demonstrates that formation of small blood vessels is impaired in the muscle tissue of postmenopausal women. The study's findings highlight the importance of physical activity for women prior to and during menopause, as a means to prevent the development of disease later in life.

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'Trojan horse' approach to kill cancer cells without using drugs

Cancer cells are killed in lab experiments and tumor growth reduced in mice, using a new approach that turns a nanoparticle into a 'Trojan horse' that causes cancer cells to self-destruct.

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Higher dementia risk in women with prolonged fertility

Women with a longer reproductive period had an elevated risk for dementia in old age, compared with those who were fertile for a shorter period, a population-based study.

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Combining two precision medicines can treat drug-resistant cancers

Launching a dual-pronged attack on tumours using a combination of two innovative precision medicines could treat patients with multiple common cancers, a new clinical trial shows.

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Botox for TMJ disorders may not lead to bone loss in the short term, but more research is needed

Botox injections to manage jaw and facial pain do not result in clinically significant changes in jaw bone when used short term and in low doses, according to researchers. However, they found evidence of bone loss when higher doses were used.

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