Potential treatment for rare degenerative disease

A pharmacology professor and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment.

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Credit-card sized tool provides new insights into how cancer cells invade host tissues

Researchers have developed a credit-card sized tool for growing cancer cells outside the human body, which they believe will enhance their understanding of breast cancer metastasis. The device reproduces various environments within the human body where breast cancer cells live. Studying the cells as they go through the process of invasion and metastasis could point the way toward new biomarkers and drugs to diagnose and treat cancer.

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Response to stimulation in IVF may predict longer term health risks

A follow-up study of almost 20,000 young women who had a first cycle of IVF in Denmark between 1995 and 2014 indicates that those who responded poorly to treatment, with few eggs collected, are at a significantly increased risk of later age-related diseases.

from Women's Health News -- ScienceDaily https://ift.tt/3ehljHp

Response to stimulation in IVF may predict longer term health risks

A follow-up study of almost 20,000 young women who had a first cycle of IVF in Denmark between 1995 and 2014 indicates that those who responded poorly to treatment, with few eggs collected, are at a significantly increased risk of later age-related diseases.

from Women's Health News -- ScienceDaily https://ift.tt/3ehljHp

New link between calcium and cardiolipin in heart defects

To function properly, the heart needs energy from cells' powerhouses, the mitochondria. In turn, mitochondria boost their energy output when calcium levels rise around them, a signal that more energy is needed. A new study shows that a shortage of cardiolipin, a type of fat, in the mitochondrial membrane, prevents calcium from entering mitochondria. The result helps explain heart and muscle weakness in the rare genetic disorder Barth syndrome.

from Women's Health News -- ScienceDaily https://ift.tt/2ChHtMu

New link between calcium and cardiolipin in heart defects

To function properly, the heart needs energy from cells' powerhouses, the mitochondria. In turn, mitochondria boost their energy output when calcium levels rise around them, a signal that more energy is needed. A new study shows that a shortage of cardiolipin, a type of fat, in the mitochondrial membrane, prevents calcium from entering mitochondria. The result helps explain heart and muscle weakness in the rare genetic disorder Barth syndrome.

from Women's Health News -- ScienceDaily https://ift.tt/2ChHtMu

One in five Georgian Londoners had syphilis by their mid-30s

250 years ago, over one-fifth of Londoners had contracted syphilis by their 35th birthday, historians have calculated.

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Coronary calcium scoring: Personalized preventive care for those most at risk

An imaging test called coronary calcium scoring can help doctors to make the right recommendation about the use of statin therapy. The test is a 10-minute CT (computed tomography) scan looking for calcium deposits in the arteries supplying blood to the heart. Calcium deposits indicate the presence of coronary plaque, also known as atherosclerosis.

from Women's Health News -- ScienceDaily https://ift.tt/3f5FZDF

Coronary calcium scoring: Personalized preventive care for those most at risk

An imaging test called coronary calcium scoring can help doctors to make the right recommendation about the use of statin therapy. The test is a 10-minute CT (computed tomography) scan looking for calcium deposits in the arteries supplying blood to the heart. Calcium deposits indicate the presence of coronary plaque, also known as atherosclerosis.

from Women's Health News -- ScienceDaily https://ift.tt/3f5FZDF

'Biologically relevant' levels of a fertility hormone are detected in human hair samples

The prospect of a non-invasive test of ovarian reserve is a little closer following results from a study showing that measurement of a fertility hormone can be accurately taken from a sample of human hair.

from Women's Health News -- ScienceDaily https://ift.tt/31NKK0A