Rapid infectious disease shifts in Chinese children and adolescents prior to COVID-19

Deaths of children and adolescents in China due to infectious diseases were becoming rare prior to the covid-19 pandemic, according to a new study.

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Experiences of undesired effects of hormonal contraception

A study of women who experienced mental ill-health from a hormonal contraception indicates they value their mental well-being higher than a satisfactory sex life. Their experiences can influence their choice of contraception. This is one of four themes that researchers have identified in interviews with 24 women who experience negative effects of some hormonal contraception.

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Consuming extra calories can help exercising women avoid menstrual disorders

Exercising women who struggle to consume enough calories and have menstrual disorders can simply increase their food intake to recover their menstrual cycle, according to a new study.

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Consuming extra calories can help exercising women avoid menstrual disorders

Exercising women who struggle to consume enough calories and have menstrual disorders can simply increase their food intake to recover their menstrual cycle, according to a new study.

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Microbiome may hold key to identifying HPV-infected women at risk for pre-cancer

Gardnerella bacteria in the cervicovaginal microbiome may serve as a biomarker to identify women infected with human papillomavirus (HPV) who are at risk for progression to precancer, according to a new study.

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Microbiome may hold key to identifying HPV-infected women at risk for pre-cancer

Gardnerella bacteria in the cervicovaginal microbiome may serve as a biomarker to identify women infected with human papillomavirus (HPV) who are at risk for progression to precancer, according to a new study.

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Experiments in mice and human cells shed light on best way to deliver nanoparticle therapy for cancer

Researchers in the cancer nanomedicine community debate whether use of tiny structures, called nanoparticles, can best deliver drug therapy to tumors passively -- allowing the nanoparticles to diffuse into tumors and become held in place, or actively -- adding a targeted anti-cancer molecule to bind to specific cancer cell receptors and, in theory, keep the nanoparticle in the tumor longer. Now, new research on human and mouse tumors in mice suggests the question is even more complicated.

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High-speed microscope captures fleeting brain signals

Neuroscientists can now capture millisecond electrical changes in neurons in the cortex of an alert mouse, allowing tracing of neural signals, including subthreshold events, in the brain. The new technique combines all-optical scanning with two-photon fluorescence imaging to produce a 2D rasterized picture every 1,000-3,000 milliseconds. That and another technique that allows 3D imaging of large areas of the mouse cortex to a depth of 650 microns will aid study of neural circuits.

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High-speed microscope captures fleeting brain signals

Neuroscientists can now capture millisecond electrical changes in neurons in the cortex of an alert mouse, allowing tracing of neural signals, including subthreshold events, in the brain. The new technique combines all-optical scanning with two-photon fluorescence imaging to produce a 2D rasterized picture every 1,000-3,000 milliseconds. That and another technique that allows 3D imaging of large areas of the mouse cortex to a depth of 650 microns will aid study of neural circuits.

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Ball-and-chain inactivation of ion channels visualized by cryo-electron microscopy

Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal 'firing' in the central nervous system and for brain and heart function. These channels use a ''ball-and-chain'' mechanism to help regulate their ion flow, according to a new study.

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