Hormone resistance in breast cancer linked to DNA 'rewiring'

Researchers have revealed changes to the 3D arrangement of DNA linked to treatment resistance in ER+ breast cancer.

from Women's Health News -- ScienceDaily https://ift.tt/38bY4vR

Pulling the plug on calcium pumps -- potential new treatment strategy for pancreatic cancer

UK scientists have identified a new way to kill pancreatic cancer cells by 'pulling the plug' on the energy generator that fuels calcium pumps on their cell surface. The study reports how switching off the cancer's energy supply causes the pancreatic cancer cells to become 'poisoned' by an irreversible build-up of calcium.

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Study shows lactate may prompt cancer formation

A byproduct of glucose called lactate, used by every cell in the body, may also prompt a mutated cell to become cancerous, according to new research.

from Breast Cancer News -- ScienceDaily https://ift.tt/3a6QJPU

DNA Damage to Breast Cells from chemicals in some cosmetics, sunscreens

A new approach to studying the effects of two common chemicals used in cosmetics and sunscreens found they can cause DNA damage in breast cells at surprisingly low concentrations, while the same dose did not harm cells without estrogen receptors.

from Women's Health News -- ScienceDaily https://ift.tt/30mGxOQ

Having less sex linked to earlier menopause

Women who engage in sexual activity weekly or monthly have a lower risk of entering menopause early relative to those who report having some form of sex less than monthly, according to a new study.

from Sexual Health News -- ScienceDaily https://ift.tt/36RTwui
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Genetic study provides most comprehensive map of risk to date of breast cancer risk

A major international study of the genetics of breast cancer has identified more than 350 DNA 'errors' that increase an individual's risk of developing the disease. The scientists involved say these errors may influence as many as 190 genes.

from Breast Cancer News -- ScienceDaily https://ift.tt/39Pg9RW

Step toward 'ink' development for 3-D printing a bioprosthetic ovary

For the first time, scientists identified and mapped the location of structural proteins in a pig ovary. Ongoing development of an 'ink' with these proteins will be used for 3-D printing an artificial (or bio-prosthetic) ovary that could be implanted and allow a woman to have a child.

from Women's Health News -- ScienceDaily https://ift.tt/35wq9My

Starting point for designing drugs that cure clostridium difficile

A new article details a research breakthrough that provides a promising starting point for scientists to create drugs that can cure C. diff -- a virulent health care-associated infection that causes severe diarrhea, nausea, internal bleeding, and potentially death.

from Women's Health News -- ScienceDaily https://ift.tt/2Fwum8J

Combining neurologic and blood pressure drugs reduces breast tumor development in mice

Adding a medication used to treat epilepsy, bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high fat diet fed to their mothers during pregnancy. Conversely, this treatment combination increased breast cancer development in the offspring whose mothers had not been fed a high fat diet during pregnancy.

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AI improves breast cancer risk prediction

A sophisticated type of artificial intelligence (AI) can outperform existing models at predicting which women are at future risk of breast cancer, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/2EB1iMK