One shot to stop HIV: MIT's bold vaccine breakthrough

Researchers from MIT and Scripps have unveiled a promising new HIV vaccine approach that generates a powerful immune response with just one dose. By combining two immune-boosting adjuvants alum and SMNP the vaccine lingers in lymph nodes for nearly a month, encouraging the body to produce a vast array of antibodies. This one-shot strategy could revolutionize how we fight not just HIV, but many infectious diseases. It mimics the natural infection process and opens the door to broadly neutralizing antibody responses, a holy grail in vaccine design. And best of all, it's built on components already known to medicine.

from Women's Health News -- ScienceDaily https://ift.tt/nTqW6LH

Complexity of tumors revealed in 3D

A new analysis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells -- and the cells of a tumor's surrounding environment -- are organized, in 3D, and how that organization changes when a tumor spreads to other organs. The detailed findings offer scientists valuable blueprints of tumors that could lead to new approaches to therapy and spark a new era in the field of cancer biology, according to the researchers.

from Breast Cancer News -- ScienceDaily https://ift.tt/fO9hbJM

Unlocking the secrets of cancer metastasis: study provides new insights, potential therapeutic opportunities

Metastasis remains the primary challenge to reducing cancer deaths worldwide. A study is providing insights that researchers say point to therapeutic opportunities.

from Breast Cancer News -- ScienceDaily https://ift.tt/kMoCjvW

Proteins and pathways involved in inflammation are associated with changes in bone mineral density over time

Researchers have found that proteins and pathways involved in inflammation are associated with changes in bone mineral density (BMD) over time. The research, could potentially lead to the identification of biomarkers that would serve as early indicators of a person's risk for bone health issues later in life.

from Women's Health News -- ScienceDaily https://ift.tt/1JxFoZB

Scientists develop scans that light-up aggressive cancer tumors for better treatment

Researchers have used a chemical compound to light up treatment-resistant cancers on imaging scans, in a breakthrough that could help medical professionals better target and treat cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/1m6Sp9v

Potential to prevent and treat a common type of inflammatory arthritis advanced by the identification of new genetic links

Researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent. This crystalline arthritis is caused by calcium pyrophosphate (CPP) crystal deposition in joints. The findings of this novel study open up promising new avenues for targeted prevention and treatment of CPPD disease, which are currently lacking.

from Women's Health News -- ScienceDaily https://ift.tt/SfEmYG4

An artificial protein that moves like something found in nature

Proteins catalyze life by changing shape when they interact with other molecules. The result is a muscle twitching, the perception of light, or a bit of energy extracted from food. The ability to engineer shapeshifting proteins opens new avenues for medicine, agriculture, and beyond.

from Women's Health News -- ScienceDaily https://ift.tt/5uRp7S9

PREVENT equation accurately estimated 10-year CVD risk and those with calcium buildup

A new risk calculator accurately identified participants who had calcium buildup in their heart arteries and those who had a higher future heart attack risk, in an analysis of about 7,000 adults in New York City referred for heart disease screening.

from Women's Health News -- ScienceDaily https://ift.tt/MCU8knJ

How molecules can 'remember' and contribute to memory and learning

Researchers have discovered how an ion channel in the brain's neurons has a kind of 'molecular memory', which contributes to the formation and preservation of lifelong memories. The researchers have identified a specific part of the ion channel at which new drugs for certain genetic diseases could be targeted.

from Women's Health News -- ScienceDaily https://ift.tt/F9nNYXH

South African study identifies two new breast cancer genes in black women

South African scientists have identified two new breast cancer genes -- RAB27A and USP22 -- in Black women, marking the first GWAS of its kind on the continent. This breakthrough highlights the need for Africa-centred genomic research and tools to improve cancer risk prediction and treatment.

from Women's Health News -- ScienceDaily https://ift.tt/H48k9rw

South African study identifies two new breast cancer genes in black women

South African scientists have identified two new breast cancer genes -- RAB27A and USP22 -- in Black women, marking the first GWAS of its kind on the continent. This breakthrough highlights the need for Africa-centred genomic research and tools to improve cancer risk prediction and treatment.

from Breast Cancer News -- ScienceDaily https://ift.tt/H48k9rw

New approach to treating aggressive breast cancers shows significant improvement in survival

A new treatment approach significantly improves survival rates for patients with aggressive, inherited breast cancers, according to researchers. In a trial where cancers were treated with chemotherapy followed by a targeted cancer drug before surgery, 100% of patients survived the critical three-year period post-surgery.

from Breast Cancer News -- ScienceDaily https://ift.tt/quIPU5k

Studies point to redlining as a 'perfect storm' for breast cancer

New research indicates that while the residential segregation policy was outlawed decades ago, it still impacts women's health today.

from Breast Cancer News -- ScienceDaily https://ift.tt/evbqOJW

Incidence rates of some cancer types have risen in people under age 50

Researchers have completed a comprehensive analysis of cancer statistics for different age groups in the United States and found that from 2010 through 2019, the incidence of 14 cancer types increased among people under age 50.

from Women's Health News -- ScienceDaily https://ift.tt/5byADor

Incidence rates of some cancer types have risen in people under age 50

Researchers have completed a comprehensive analysis of cancer statistics for different age groups in the United States and found that from 2010 through 2019, the incidence of 14 cancer types increased among people under age 50.

from Breast Cancer News -- ScienceDaily https://ift.tt/5byADor

Incidence of several early-onset cancers increased between 2010 and 2019

In the United States, breast, colorectal, endometrial, pancreatic, and kidney cancers are becoming increasingly common among people under age 50, according to a new study.

from Breast Cancer News -- ScienceDaily https://ift.tt/lBdRePm

Incidence of several early-onset cancers increased between 2010 and 2019

In the United States, breast, colorectal, endometrial, pancreatic, and kidney cancers are becoming increasingly common among people under age 50, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/lBdRePm

Removing ovaries and fallopian tubes linked to lower risk of early death among breast cancer patients with BRCA cancer genes

Women diagnosed with breast cancer who carry particular BRCA1 and BRCA2 genetic variants are offered surgery to remove the ovaries and fallopian tubes as this dramatically reduces their risk of ovarian cancer. Now, researchers have shown that this procedure -- known as bilateral salpingo-oophorectomy (BSO) -- is associated with a substantial reduction in the risk of early death among these women, without any serious side-effects.

from Women's Health News -- ScienceDaily https://ift.tt/uMkfTZ8

Removing ovaries and fallopian tubes linked to lower risk of early death among breast cancer patients with BRCA cancer genes

Women diagnosed with breast cancer who carry particular BRCA1 and BRCA2 genetic variants are offered surgery to remove the ovaries and fallopian tubes as this dramatically reduces their risk of ovarian cancer. Now, researchers have shown that this procedure -- known as bilateral salpingo-oophorectomy (BSO) -- is associated with a substantial reduction in the risk of early death among these women, without any serious side-effects.

from Breast Cancer News -- ScienceDaily https://ift.tt/uMkfTZ8

AI-human task-sharing could cut mammography screening costs by up to 30%

The most effective way to harness the power of artificial intelligence when screening for breast cancer may be through collaboration with human radiologists -- not by wholesale replacing them, says new research.

from Breast Cancer News -- ScienceDaily https://ift.tt/4bvluYU

AI could help improve early detection of interval breast cancers

A new study suggests that artificial intelligence (AI) could help detect interval breast cancers before they become more advanced and harder to treat.

from Breast Cancer News -- ScienceDaily https://ift.tt/veTWD2m

Drug combination reduces breast cancer risk and improves metabolic health in rats

Researchers investigated the combined effects of bazedoxifene and conjugated estrogens in rat models as an alternative to tamoxifen.

from Breast Cancer News -- ScienceDaily https://ift.tt/7v2XGWz

Low iron could cause brain fog during menopause transition

New research sheds light on an understudied area of science: iron levels in the blood and their relationship to cognitive performance in women transitioning into menopause. The findings are good news for women experiencing brain fog and other symptoms.

from Women's Health News -- ScienceDaily https://ift.tt/h2FL1O3

Breast cancer mortality in women ages 20-49 significantly dropped between 2010 and 2020

Breast cancer deaths among women ages 20-49 declined significantly between 2010 and 2020, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/03jS4sy

Breast cancer mortality in women ages 20-49 significantly dropped between 2010 and 2020

Breast cancer deaths among women ages 20-49 declined significantly between 2010 and 2020, according to a new study.

from Breast Cancer News -- ScienceDaily https://ift.tt/03jS4sy

New machine algorithm could identify cardiovascular risk at the click of a button

An automated machine learning program has been able to identify potential cardiovascular incidents or fall and fracture risks based on bone density scans taken during routine clinical testing.

from Women's Health News -- ScienceDaily https://ift.tt/z2uKjHP

Can hormone therapy improve heart health in menopausal women?

Oral hormone therapy may benefit heart health in menopausal women. A new analysis of data from the Women's Health Initiative found that estrogen-based oral hormone therapy had a long-term beneficial effect on biomarkers of cardiovascular health, including cholesterol.

from Women's Health News -- ScienceDaily https://ift.tt/roFt3Ha

Telehealth might be a good option for women with incontinence

Women who experience urinary incontinence after giving birth may get just as much relief from telehealth as they do from physical therapy, a new study has found.

from Women's Health News -- ScienceDaily https://ift.tt/ysBPQXD

Menopause at an early age can exacerbate cognitive decline

Why does dementia affect more women than men? To help solve this mystery, researchers uncovered a new risk factor: age of menopause onset.

from Women's Health News -- ScienceDaily https://ift.tt/q4Vou3g

Researchers report association between urinary incontinence, cardiovascular disease

Researchers report an association between urinary incontinence and cardiovascular disease risk in women. The researcher recommend women should be checked regularly for urinary incontinence.

from Women's Health News -- ScienceDaily https://ift.tt/i6879AF

Are high support bras bad for the back?

Researchers uncover how over-reducing breast motion in bras could increase back pain during exercise.

from Women's Health News -- ScienceDaily https://ift.tt/4FaOlXe

Running on empty: Poor nutrition increases injury risk for female athletes

Proper nutrition is crucial for enhancing athletic performance, supporting recovery and overall health. Now, a new study reveals that proper nutrition is also key to reducing risk of injury, especially for females.

from Women's Health News -- ScienceDaily https://ift.tt/vkx7OQp

Discovery of mitochondrial protein opens path to therapeutic advances for heart and Alzheimer's disease

Calcium transport into and out of mitochondria -- the powerhouses of cells -- is central to cellular energy production and cell death. To maintain the balance of calcium within these powerhouses, cells rely on a protein known as the mitochondrial sodium-calcium exchanger, or NCLX. Now, in new research, scientists have discovered a novel regulator of NCLX activity, a protein called TMEM65, which helps move calcium out of mitochondria, protecting against harmful calcium overload.

from Women's Health News -- ScienceDaily https://ift.tt/PVpoOhn

Estrogen and progesterone stimulate the body to make opioids

Female hormones can suppress pain by making immune cells near the spinal cord produce opioids, a new study has found. This stops pain signals before they get to the brain. The discovery could help with developing new treatments for chronic pain. It may also explain why some painkillers work better for women than men and why postmenopausal women experience more pain.

from Women's Health News -- ScienceDaily https://ift.tt/KeZTUr7

Rates of breast and colorectal cancer screening nearly four-fold higher than lung cancer screening among those eligible

Lung cancer screening has the potential to catch lung cancer early and save lives -- but only if people get screened. Although lung cancer screening is recommended in the U.S. for certain individuals with a history of smoking, only 18% of eligible individuals in the U.S. get screened. One suggested explanation has been that those eligible are resistant to receiving preventive healthcare, but a new study indicates otherwise.

from Breast Cancer News -- ScienceDaily https://ift.tt/fJUP0O5

Omega-6 fatty acid promotes the growth of an aggressive type of breast cancer, study finds

Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat 'triple negative' breast cancer subtype, according to a preclinical study. The discovery could lead to new dietary and pharmaceutical strategies against breast and other cancers.

from Breast Cancer News -- ScienceDaily https://ift.tt/v0aCfAw

Omega-6 fatty acid promotes the growth of an aggressive type of breast cancer, study finds

Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat 'triple negative' breast cancer subtype, according to a preclinical study. The discovery could lead to new dietary and pharmaceutical strategies against breast and other cancers.

from Women's Health News -- ScienceDaily https://ift.tt/v0aCfAw

How a Y chromosome gene may shape the course of heart valve disease

Researchers have shed new light on how a type of heart valve disease -- aortic valve stenosis -- progresses differently in males and females.

from Women's Health News -- ScienceDaily https://ift.tt/hrFNdgq

AI-powered mammograms: A new window into heart health

Mammograms, with the help of artificial intelligence (AI) models, may reveal much more than cancer, according to a new study. The findings highlight how these important cancer screening tools can also be used to assess the amount of calcium buildup in the arteries within breast tissue -- an indicator of cardiovascular health.

from Breast Cancer News -- ScienceDaily https://ift.tt/nMjSoTe

Vaccine may improve breast cancer treatment outcomes

Researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer. The innovative approach targets human epidermal growth factor receptor 2-positive, estrogen receptor-negative (HER2-positive, ER-negative) breast cancer and has shown encouraging results in a recent pilot study. The study combined the HER2-targeting dendritic cell vaccines with standard chemotherapy, demonstrating both safety and positive response rates.

from Breast Cancer News -- ScienceDaily https://ift.tt/E1SqgKG

Vaccine may improve breast cancer treatment outcomes

Researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer. The innovative approach targets human epidermal growth factor receptor 2-positive, estrogen receptor-negative (HER2-positive, ER-negative) breast cancer and has shown encouraging results in a recent pilot study. The study combined the HER2-targeting dendritic cell vaccines with standard chemotherapy, demonstrating both safety and positive response rates.

from Women's Health News -- ScienceDaily https://ift.tt/E1SqgKG

Slow, silent 'scream' of epithelial cells detected for first time

It has long been thought that only nerve and heart cells use electric impulses to communicate, while epithelial cells -- which compose the linings of our skin, organs and body cavities -- are mute, serving mostly as protective barriers that can absorb and secrete various substances. But researchers have now upended the status quo by showing that epithelial cells do indeed 'talk' to each other, albeit with slow electrical signals.

from Women's Health News -- ScienceDaily https://ift.tt/A0GRJxm

Oxytocin system of breastfeeding affected in mothers with postnatal depression

The oxytocin system -- which helps release breast milk and strengthens the bond between mother and baby -- may be affected during breastfeeding in mothers experiencing postnatal depression.

from Women's Health News -- ScienceDaily https://ift.tt/7Ej6UHh

New antibody reduces tumor growth in treatment-resistant breast and ovarian cancers

A new type of antibody which stimulates the immune system to target cancer cells slows tumour growth, according to new research.

from Breast Cancer News -- ScienceDaily https://ift.tt/p5wl9ta

Nwd1 gene deletion triggers MASH-like pathology in mice

Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their specific roles in the progression of disease remain unknown. To address this gap, researchers conducted a series of experiments that identified the NACHT and WD repeat domain-containing protein 1 (Nwd1) gene and its role in liver pathogenesis. This breakthrough represents an important step toward establishing new therapeutic targets for MASH.

from Women's Health News -- ScienceDaily https://ift.tt/x4tPIUk

Exercise and healthy eating behavior together provide the best protection against cardiovascular diseases

Researchers have found that women who exhibit disturbed eating behaviors and engage in low physical activity tend to have more central body fat and a higher risk of metabolic low-grade inflammation. This condition increases the risk of cardiovascular diseases, which become more prevalent after menopause. However, the combined effect of exercise and healthy eating behavior offers the most effective protection against inflammation and may also reduce it after menopause.

from Women's Health News -- ScienceDaily https://ift.tt/CnuYNQ1

Diabetes drug could help cancer patients make better recovery

Research shows that a common type of diabetes medication could help cancer patients make a better long-term recovery. Many cancer patients go on to develop heart failure -- because of the cancer itself and also due to chemotherapy. But a study shows that a type of diabetes drug, called an SGLT2 inhibitor, may help protect the heart during and after cancer treatment. The medication has been shown to be beneficial in reducing heart failure or heart failure hospitalisation in cancer patients and survivors.

from Breast Cancer News -- ScienceDaily https://ift.tt/oLv4nJC

Links between metabolism and aggressive breast cancer

More than 120 million Americans suffer from diabetes or pre-diabetes. Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer, and TNBC patients with obesity-driven diabetes often have worse outcomes. A new study helps explain why this happens and suggests a potential way to improve treatment for these patients.

from Breast Cancer News -- ScienceDaily https://ift.tt/EOvH92t

Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure

The discovery of a novel approach to promote cardiomyocyte proliferation offers new hope for the treatment of ischemic heart failure.

from Women's Health News -- ScienceDaily https://ift.tt/2banWBP

Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure

The discovery of a novel approach to promote cardiomyocyte proliferation offers new hope for the treatment of ischemic heart failure.

from Women's Health News -- ScienceDaily https://ift.tt/6qTFDl7

Scientists upends scientific understanding of how anticancer drugs kill cancer

BRCA1 and BRCA2 genes play a crucial role in repairing damaged DNA. Mutations in BRCA1 and BRCA2 substantially increase the likelihood of breast and ovarian cancer, respectively. This new research illustrates how small breaks in one strand of DNA can expand into a large single-stranded DNA gap that kills drug-resistant breast BRCA mutant cancer cells. The novel vulnerability in mutant BRCA1 and BRCA2 may be a potential target for new therapeutics.

from Breast Cancer News -- ScienceDaily https://ift.tt/RvgekUr

Future drugs may snap supply chain fueling breast cancer

Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells hijack various cellular functions to find and exploit energy and other resources, including a group of enzymes that help normal cells maintain a balance of energy. These enzymes, called creatine kinases (CK), allow cells to transport energy produced at the mitochondria to where it is needed throughout the cell. Studies of breast cancer cells have highlighted the importance of a type of CK called ubiquitous mitochondrial creatine kinase (uMtCK).

from Breast Cancer News -- ScienceDaily https://ift.tt/ifdCjsm

Study establishes 'ball and chain' mechanism inactivates key mammalian ion channel

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a 'ball-and-chain' channel-plugging mechanism. The findings boost the understanding of ion channel biology and could lead to new drugs that target these channels to treat disorders such as epilepsy and hypertension.

from Women's Health News -- ScienceDaily https://ift.tt/vP7xyXo

Researchers unravel menopause timing, shedding light on ovarian aging and fertility

The research team has developed a theoretical framework that quantitatively predicts menopause timing. By analyzing how ovarian follicles transition through different stages, the researchers' model explains why menopause occurs and sheds light on individual variability and cross-population differences. These insights could improve fertility planning, inform health care decisions related to hormonal therapies and enhance our understanding of age-related health risks associated with ovarian aging.

from Women's Health News -- ScienceDaily https://ift.tt/9BaitzY

Researchers develop novel computational approach for identifying synergistic drug combinations

Researchers have developed a powerful computational tool, named iDOMO, to improve the prediction of drug synergy and accelerate the development of combination therapies for complex diseases. The study highlights iDOMO's ability to identify synergistic drug combinations using gene expression data, outperforming existing methods.

from Breast Cancer News -- ScienceDaily https://ift.tt/yaDRbvP

Data from all 50 states shows early onset breast cancer is on the rise in younger women: Does place of exposure matter?

Breast cancer incidence trends in U.S. women under 40 vary by geography and supports incorporating location information with established risk factors into risk prediction, improving the ability to identify groups of younger women at higher risk for early-onset breast cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/7MER0io

Data from all 50 states shows early onset breast cancer is on the rise in younger women: Does place of exposure matter?

Breast cancer incidence trends in U.S. women under 40 vary by geography and supports incorporating location information with established risk factors into risk prediction, improving the ability to identify groups of younger women at higher risk for early-onset breast cancer.

from Women's Health News -- ScienceDaily https://ift.tt/7MER0io

Nerves electrify stomach cancer, sparking growth and spread

Researchers have found that a cancer outside the brain makes electrical connections with the nervous system to fuel cancer growth and aid its spread.

from Women's Health News -- ScienceDaily https://ift.tt/wyC8IHc

Speculum exams unnecessary for HPV screening

Researchers have demonstrated that self-sampling is just as effective as speculum-based testing for HPV detection.

from Women's Health News -- ScienceDaily https://ift.tt/uVnFPf3

Sweet taste receptors in the heart: A new pathway for cardiac regulation

In a surprising discovery, scientists have found that the heart possesses 'sweet taste' receptors, similar to those on our tongues, and that stimulating these receptors with sweet substances can modulate the heartbeat. This research opens new avenues for understanding heart function and potentially for developing novel treatments for heart failure.

from Women's Health News -- ScienceDaily https://ift.tt/CysnXNq

Landmark atlas reveals how aging breast tissue shapes breast cancer risk

Aging is a privilege, but it also brings risks -- including an increased likelihood of developing age-related diseases including cancer. Researchers have now created a landmark atlas of how healthy breast tissue ages, revealing key cellular, molecular, and genetic changes that may tip the balance toward breast cancer development.

from Women's Health News -- ScienceDaily https://ift.tt/Gk7l02f

Landmark atlas reveals how aging breast tissue shapes breast cancer risk

Aging is a privilege, but it also brings risks -- including an increased likelihood of developing age-related diseases including cancer. Researchers have now created a landmark atlas of how healthy breast tissue ages, revealing key cellular, molecular, and genetic changes that may tip the balance toward breast cancer development.

from Breast Cancer News -- ScienceDaily https://ift.tt/Gk7l02f

Disordered eating and certain foods linked to higher risk for urinary incontinence in middle-aged women

Eating behavior is associated with symptoms of pelvic floor disorders in middle-aged women. For example, higher consumption of highly processed ready-made foods and fast food increased the risk for experiencing symptoms of stress and urgency urinary incontinence. Higher consumption of fruits and an overall higher quality diet decreased the risk for stress urinary incontinence.

from Women's Health News -- ScienceDaily https://ift.tt/rgZfWEB

Innovative dual-target drug may lead to new investigational approach for breast cancer patients

Researchers discover new insights into how dual-target drug may supercharge cancer-fighting immune cells.

from Breast Cancer News -- ScienceDaily https://ift.tt/e8RShIa

Ovarian cancer discovery could turn failed treatment into lifesaver

Gut bacteria are to blame for the failure of immune checkpoint therapy for ovarian cancer, new research reveals.

from Women's Health News -- ScienceDaily https://ift.tt/sD6Ii7n

Disruption of a single amino acid in a cellular protein makes breast cancer cells behave like stem cells

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long noncoding RNA (lncRNA) 'XIST' could be an effective therapeutic strategy for treating aggressive breast cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/d9T0aZA

Breast cancers broadly defined by their genome architecture

Breast cancers at all stages are defined by the structure of their genomes, researchers find. Targeting these processes early is likely to offer unexpected therapeutic avenues.

from Women's Health News -- ScienceDaily visit

Breast cancers broadly defined by their genome architecture

Breast cancers at all stages are defined by the structure of their genomes, researchers find. Targeting these processes early is likely to offer unexpected therapeutic avenues.

from Breast Cancer News -- ScienceDaily https://ift.tt/U4wnRoy

Drug may counteract muscle loss and osteoporosis after rapid weight loss

Rapid weight loss affects muscle mass and can increase the risk of osteoporosis. But now there is good news for people taking weight loss medication who may be at risk. A new study indicates that the drug bimagrumab can counteract the side effects.

from Women's Health News -- ScienceDaily https://ift.tt/gvlUcxW

From muscle to memory: New research uses clues from the body to understand signaling in the brain

New research shows that a network of subcellular structures similar to those responsible for propagating molecular signals that make muscles contract are also responsible for transmitting signals in the brain that may facilitate learning and memory.

from Women's Health News -- ScienceDaily https://ift.tt/K062oVt

Fear of breast cancer recurrence: Impact and coping with being in a dark place

A new study of breast cancer survivors has found this psychosocial challenge impacts almost every important domain of their lives -- the emotional, behavioral, cognitive, relational and professional. A larger number of domains was affected, and they were affected more frequently in those with greater fear of recurrence. The majority of study participants indicated that they sought senses of purpose, belonging, control and connection with others.

from Breast Cancer News -- ScienceDaily https://ift.tt/cl4VxNq

Later-onset menopause linked to healthier blood vessels, lower heart disease risk

New research shows that women who hit menopause later in life have healthier blood vessels and mitochondria and a different composition of metabolites in their blood than those who stop menstruating earlier. The study helps explain why late-onset menopause is linked to lower risk of heart attacks and strokes.

from Women's Health News -- ScienceDaily https://ift.tt/FV3RpNy

Communication between body muscle and the brain influences fertility

A newly discovered line of communication between body muscle and the pituitary gland may play an unexpected role in female fertility, according to a new study. Researchers found that a protein produced in the muscles helps manage the release of a hormone made in the pea-sized gland attached to the base of the brain.

from Women's Health News -- ScienceDaily https://ift.tt/DvXxK79

How hungry fat cells could someday starve cancer to death

Liposuction and plastic surgery aren't often mentioned in the same breath as cancer. But they are the inspiration for a new approach to treating cancer that uses engineered fat cells to deprive tumors of nutrition. Researchers at UC San Francisco used the gene editing technology CRISPR to turn ordinary white fat cells into 'beige' fat cells, which voraciously consume calories to make heat.

from Breast Cancer News -- ScienceDaily https://ift.tt/WXIR60a

Inhibitor drugs to treat aggressive breast cancer identified

A national study seeking more effective treatment for deadly metaplastic breast cancer has identified two inhibitor drugs with the potential to interrupt disease progression.

from Breast Cancer News -- ScienceDaily https://ift.tt/z3SJk9w

Removing fallopian tubes during other abdominal surgeries may lower ovarian cancer risk

A mathematical modeling study suggests that ovarian cancer incidence could be reduced and healthcare savings boosted if women who have already completed their families were offered fallopian tube removal during any other suitable abdominal surgeries.

from Women's Health News -- ScienceDaily https://ift.tt/Unka90l

Study shows potential of resveratrol to aid fertility

A new study has highlighted the potential of resveratrol, a natural compound found in grapes, blueberries, and raspberries, to enhance female fertility. The systematic review found that resveratrol can improve the quantity and quality of egg cells, offering hope for new, less invasive fertility treatments.

from Women's Health News -- ScienceDaily https://ift.tt/YkU24pP

An injectable hydrogel for local bone densification

Researchers have combined injections of a novel hydrogel with systemic osteoporosis drugs in rats, achieving rapid local increases in bone density. The results offer hope for future fracture prevention therapies in osteoporosis patients.

from Women's Health News -- ScienceDaily https://ift.tt/NyaVwlY

Routine brain MRI screening in asymptomatic late stage breast cancer patients

A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study suggests that doctors may need to rethink current screening guidelines for detecting brain metastasis in patients without symptoms.

from Breast Cancer News -- ScienceDaily https://ift.tt/K9jfOJI

Inherited gene elevates prostate cancer risk in affected families

The inherited mutated gene WNT9B, which functions normally in embryonic prostate development, increases risk of adult prostate cancer, according to a new study.

from Breast Cancer News -- ScienceDaily https://ift.tt/GIkfdB9

Dissolving clusters of cancer cells to prevent metastases

Successful test in breast cancer patients: the active agent digoxin, a cardiac medication, dissolves clusters of circulating breast cancer cells in the blood, thus reducing the risk of metastases formation.

from Breast Cancer News -- ScienceDaily https://ift.tt/oz36fCY

Dissolving clusters of cancer cells to prevent metastases

Successful test in breast cancer patients: the active agent digoxin, a cardiac medication, dissolves clusters of circulating breast cancer cells in the blood, thus reducing the risk of metastases formation.

from Women's Health News -- ScienceDaily https://ift.tt/oz36fCY

New combination immunotherapy for melanoma and breast cancer

A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod. This combination showed promising results in topically accessible tumors like melanoma and breast cancer models: The therapy led to the death of tumor cells at the treated sites and simultaneously activated the adaptive immune system to fight even distant metastases. The results could improve the treatment of superficial tumors such as melanoma and breast cancer.

from Women's Health News -- ScienceDaily https://ift.tt/Gj2AF3k

New combination immunotherapy for melanoma and breast cancer

A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod. This combination showed promising results in topically accessible tumors like melanoma and breast cancer models: The therapy led to the death of tumor cells at the treated sites and simultaneously activated the adaptive immune system to fight even distant metastases. The results could improve the treatment of superficial tumors such as melanoma and breast cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/Gj2AF3k

Drug candidate eliminates breast cancer tumors in mice in a single dose

Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late effects of these treatments include osteoporosis, sexual dysfunction and blood clots. Now, researchers have created a novel treatment that eliminated small breast tumors and significantly shrank large tumors in mice in a single dose, without problematic side effects.

from Breast Cancer News -- ScienceDaily https://ift.tt/mt98gEp

Drug candidate eliminates breast cancer tumors in mice in a single dose

Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late effects of these treatments include osteoporosis, sexual dysfunction and blood clots. Now, researchers have created a novel treatment that eliminated small breast tumors and significantly shrank large tumors in mice in a single dose, without problematic side effects.

from Women's Health News -- ScienceDaily https://ift.tt/mt98gEp

Telephone therapy reduces fatigue interference with activities, mood and cognition for metastatic breast cancer survivors

A clinical trial demonstrates the effectiveness of telephone-delivered acceptance and commitment therapy (ACT) in reducing fatigue's interference with functioning and improving the quality of life for survivors of metastatic breast cancer. The ACT intervention helped study participants to fall asleep with greater ease. Fatigue remains a significant challenge for these survivors, affecting up to 63 percent of patients and severely impacting daily functioning.

from Breast Cancer News -- ScienceDaily https://ift.tt/ESKTyXU

Rotavirus protein NSP4 manipulates gastrointestinal disease severity

Researchers have improved our understanding of how rotavirus, the most common cause of acute gastroenteritis in children, makes people sick. The study is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells. These disruptions in calcium signaling affect rotavirus disease severity, providing new insights into how NSP4's function influences rotavirus virulence. The findings suggest that manipulating NSP4 could lead to new strategies to prevent or treat rotavirus infections.

from Women's Health News -- ScienceDaily https://ift.tt/xXwb71i

Drug in clinical trials for breast cancer could also treat some blood cancers

Two new studies have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials against breast cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/RCYGp5Q

Cancer mortality continues to drop despite rising incidence in women

The American Cancer Society (ACS) today released Cancer Statistics, 2025, the organization's annual report on cancer facts and trends. The new findings show the cancer mortality rate declined by 34% from 1991 to 2022 in the United States, averting approximately 4.5 million deaths. However, this steady progress is jeopardized by increasing incidence for many cancer types, especially among women and younger adults, shifting the burden of disease. For example, incidence rates in women 50-64 years of age have surpassed those in men, and rates in women under 50 are now 82% higher than their male counterparts, up from 51% in 2002.

from Women's Health News -- ScienceDaily https://ift.tt/dXi7UFP

Researchers resolve uncertainty in BRCA2 testing, improving cancer risk assessment and patient care

Findings from a multi-institutional, international study have significantly advanced the understanding of genetic alterations in the BRCA2 gene, a key player in hereditary cancer risk.

from Breast Cancer News -- ScienceDaily https://ift.tt/Dg4wEQZ

Researchers boost chemotherapy uptake in breast cancer treatment with localized magnetic fields

Researchers have developed a non-invasive method to improve the effectiveness of chemotherapy while reducing its harmful side effects. By applying brief, localized pulses of magnetic fields, the team demonstrated a significant increase in the uptake of doxorubicin (DOX), a widely used chemotherapy drug, into breast cancer cells, with minimal impact on healthy tissues.

from Breast Cancer News -- ScienceDaily https://ift.tt/nla37qw

Researchers boost chemotherapy uptake in breast cancer treatment with localized magnetic fields

Researchers have developed a non-invasive method to improve the effectiveness of chemotherapy while reducing its harmful side effects. By applying brief, localized pulses of magnetic fields, the team demonstrated a significant increase in the uptake of doxorubicin (DOX), a widely used chemotherapy drug, into breast cancer cells, with minimal impact on healthy tissues.

from Women's Health News -- ScienceDaily https://ift.tt/nla37qw

Approaches against metastatic breast cancer: mini-tumors from circulating cancer cells

Tumor cells circulating in the blood are the 'germ cells' of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy resistance difficult. A team has now succeeded for the first time in cultivating stable tumor organoids directly from blood samples of breast cancer patients. Using these mini-tumors, the researchers were able to decipher a molecular signaling pathway that ensures the cancer cells' survival and resistance to therapy. With this knowledge, the team was able to develop an approach to specifically eliminate these tumor cells in lab experiments.

from Breast Cancer News -- ScienceDaily https://ift.tt/Rafn5pw

Patients with heart disease may be at increased risk for advanced breast cancer

Patients diagnosed with late-stage or metastatic breast cancer have a statistically significant increased risk of pre-diagnosis cardiovascular disease (CVD) compared to those with early-stage cancer at diagnosis.

from Breast Cancer News -- ScienceDaily https://ift.tt/5O8fIXk

Patients with heart disease may be at increased risk for advanced breast cancer

Patients diagnosed with late-stage or metastatic breast cancer have a statistically significant increased risk of pre-diagnosis cardiovascular disease (CVD) compared to those with early-stage cancer at diagnosis.

from Women's Health News -- ScienceDaily https://ift.tt/5O8fIXk

Achieving bone regeneration and adhesion with harmless visible light

A team develops an innovative injectable hydrogel for bone regeneration, addressing the limitations of traditional bone grafts and adhesion methods.

from Women's Health News -- ScienceDaily https://ift.tt/u0biAyq