Cystic fibrosis drug could help treat pneumonia

Pathogens such as SARS-CoV-2 and pneumococcus can cause severe pneumonia. If the airways then fill with fluid, the patient risks developing acute respiratory distress syndrome. Researchers have now discovered the molecular mechanisms that trigger fluid accumulation in the lungs. This also led them to discover a potential new therapy: A cystic fibrosis drug proved effective in their laboratory experiments, raising hope that this could be used to treat pneumonia regardless of the pathogen that caused it.

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High-energy X-rays leave a trace of destruction in bone collagen

A team of medical researchers has analyzed damage by focused high energetic X-rays in bone samples from fish and mammals at BESSY II. With a combination of microscopy techniques, the scientists could document the destruction of collagen fibers induced by electrons emitted from the mineral crystals. X-ray methods might impact bone samples when measured for a long time they conclude.

from Women's Health News -- ScienceDaily https://ift.tt/HLO8nIX

High-energy X-rays leave a trace of destruction in bone collagen

A team of medical researchers has analyzed damage by focused high energetic X-rays in bone samples from fish and mammals at BESSY II. With a combination of microscopy techniques, the scientists could document the destruction of collagen fibers induced by electrons emitted from the mineral crystals. X-ray methods might impact bone samples when measured for a long time they conclude.

from Women's Health News -- ScienceDaily https://ift.tt/HLO8nIX

High doses of statins increase osteoporosis risk, shows study in animals

An animal experiment demonstrates what big data analysis previously indicated: high doses of statins likely increase osteoporosis risk.

from Women's Health News -- ScienceDaily https://ift.tt/a7FI1lA

Subcutaneous fat emerges as a protector of females' brains

Females' propensity to deposit more fat in places like their hips, buttocks and the backs of their arms, so-called subcutaneous fat, is protective against brain inflammation, which can result in problems like dementia and stroke, at least until menopause, scientists report.

from Women's Health News -- ScienceDaily https://ift.tt/D8gtimV

Subcutaneous fat emerges as a protector of females' brains

Females' propensity to deposit more fat in places like their hips, buttocks and the backs of their arms, so-called subcutaneous fat, is protective against brain inflammation, which can result in problems like dementia and stroke, at least until menopause, scientists report.

from Women's Health News -- ScienceDaily https://ift.tt/D8gtimV

Who is more prone to recurrent UTIs? Bladder bacteria may be key

Researchers have identified specific bacteria in the bladder that may indicate which postmenopausal women are more susceptible to recurrent urinary tract infections (UTIs), and they found that estrogen may play a role in reducing that susceptibility.

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Who is more prone to recurrent UTIs? Bladder bacteria may be key

Researchers have identified specific bacteria in the bladder that may indicate which postmenopausal women are more susceptible to recurrent urinary tract infections (UTIs), and they found that estrogen may play a role in reducing that susceptibility.

from Women's Health News -- ScienceDaily https://ift.tt/qsbmy8J

Estrogen may offer protection against delirium

Delirium is common among women with urinary tract infections (UTIs) -- especially those who have experienced menopause. Investigators, working with laboratory mice, have been able to prevent symptoms of the condition with estrogen, which is commonly used for hormone replacement therapy.

from Women's Health News -- ScienceDaily https://ift.tt/8evZNbI

Estrogen may offer protection against delirium

Delirium is common among women with urinary tract infections (UTIs) -- especially those who have experienced menopause. Investigators, working with laboratory mice, have been able to prevent symptoms of the condition with estrogen, which is commonly used for hormone replacement therapy.

from Women's Health News -- ScienceDaily https://ift.tt/8evZNbI

Women with elevated breast cancer risk could see mortality benefit from estrogen-blocking drugs

While it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developing new breast cancers, a new computer modeling study has shown that these treatments could also reduce the risk of dying from the disease in women who are at high risk.

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Study in mice suggests that expression of estrogen-related gene can impact post-menopausal breast cancer risk and prevention strategies

In a study using a mouse model of aging that mimics breast cancer development in estrogen receptor-positive post-menopausal women, investigators have determined that over-expression, or switching on of the Esr1 gene, could lead to elevated risk of developing estrogen receptor-positive breast cancer in older women.

from Breast Cancer News -- ScienceDaily https://ift.tt/Lz30Hml

Study in mice suggests that expression of estrogen-related gene can impact post-menopausal breast cancer risk and prevention strategies

In a study using a mouse model of aging that mimics breast cancer development in estrogen receptor-positive post-menopausal women, investigators have determined that over-expression, or switching on of the Esr1 gene, could lead to elevated risk of developing estrogen receptor-positive breast cancer in older women.

from Women's Health News -- ScienceDaily https://ift.tt/Lz30Hml