New relevant target for PARP inhibitor talazoparib

Researchers report the identification of a new target for the PARP inhibitor drug talazoparib and show that combination treatment with talazoparib and the WEE1 inhibitor adavosertib results in enhanced anti-cancer effects.

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Heart cell protein could lead to new treatments for heart failure and recovery

A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, according to a new study.

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Heart cell protein could lead to new treatments for heart failure and recovery

A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/3leJ1LP

Seeking a unique treatment for lobular breast cancer

In an attempt to find out why the long-term outcomes are poorer for patients with lobular breast cancer -- which affects some 40,000 women a year -- researchers began looking at the role of the protein MDC1 in tumor cells.

from Women's Health News -- ScienceDaily https://ift.tt/2V2xWCy

Postmenopausal women can dance their way to better health

Women often struggle with managing their weight and other health risk factors, such as high cholesterol, once they transition through menopause. A new study suggests that dancing may effectively lower cholesterol levels, improve fitness and body composition and in the process, improve self-esteem.

from Women's Health News -- ScienceDaily https://ift.tt/2WviSxU

Seeking a unique treatment for lobular breast cancer

In an attempt to find out why the long-term outcomes are poorer for patients with lobular breast cancer -- which affects some 40,000 women a year -- researchers began looking at the role of the protein MDC1 in tumor cells.

from Women's Health News -- ScienceDaily https://ift.tt/2V2xWCy

Postmenopausal women can dance their way to better health

Women often struggle with managing their weight and other health risk factors, such as high cholesterol, once they transition through menopause. A new study suggests that dancing may effectively lower cholesterol levels, improve fitness and body composition and in the process, improve self-esteem.

from Women's Health News -- ScienceDaily https://ift.tt/2WviSxU

Seeking a unique treatment for lobular breast cancer

In an attempt to find out why the long-term outcomes are poorer for patients with lobular breast cancer -- which affects some 40,000 women a year -- researchers began looking at the role of the protein MDC1 in tumor cells.

from Breast Cancer News -- ScienceDaily https://ift.tt/2V2xWCy

New approach eradicates breast cancer in mice

A new approach to treating breast cancer kills 95 to 100 percent of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels.

from Women's Health News -- ScienceDaily https://ift.tt/3y4EA9O

New approach eradicates breast cancer in mice

A new approach to treating breast cancer kills 95 to 100 percent of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels.

from Breast Cancer News -- ScienceDaily https://ift.tt/3y4EA9O

New approach eradicates breast cancer in mice

A new approach to treating breast cancer kills 95 to 100 percent of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels.

from Women's Health News -- ScienceDaily https://ift.tt/3y4EA9O

Study finds calcium precisely directs blood flow in the brain

Researchers have shown how the brain communicates to blood vessels when in need of energy, and how these blood vessels respond by relaxing or constricting to direct blood flow to specific brain regions.

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Study finds calcium precisely directs blood flow in the brain

Researchers have shown how the brain communicates to blood vessels when in need of energy, and how these blood vessels respond by relaxing or constricting to direct blood flow to specific brain regions.

from Women's Health News -- ScienceDaily https://ift.tt/3y0moyb

Cognitive decline may help predict future fracture risk in women

A 16-year study has revealed a link between cognitive decline, bone loss and fracture risk in women.

from Women's Health News -- ScienceDaily https://ift.tt/3iB4WcP

Cognitive decline may help predict future fracture risk in women

A 16-year study has revealed a link between cognitive decline, bone loss and fracture risk in women.

from Women's Health News -- ScienceDaily https://ift.tt/3iB4WcP

Unleashing Treg cells may lead to treatments for multiple sclerosis

In a new study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

from Women's Health News -- ScienceDaily https://ift.tt/3BqhKvu

Unleashing Treg cells may lead to treatments for multiple sclerosis

In a new study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

from Women's Health News -- ScienceDaily https://ift.tt/3BqhKvu

Mechanisms to separately regulate synaptic vesicle release and recycling

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses.

from Women's Health News -- ScienceDaily https://ift.tt/3xQbmex

Mechanisms to separately regulate synaptic vesicle release and recycling

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses.

from Women's Health News -- ScienceDaily https://ift.tt/3xQbmex

New study links moderate alcohol use with higher cancer risk

A new study has found an association between alcohol and a substantially higher risk of several forms of cancer, including breast, colon, and oral cancers. Increased risk was evident even among light to moderate drinkers (up to two drinks a day), who represented 1 in 7 of all new cancers in 2020 and more than 100,000 cases worldwide.

from Breast Cancer News -- ScienceDaily https://ift.tt/3r7D6sG

A step toward advancing precision hormone therapies to reduce Alzheimer's risk

When it comes to post-menopausal hormone therapy, the type, route and duration all play a role in reducing the risk of neurodegenerative diseases.

from Women's Health News -- ScienceDaily https://ift.tt/3yRJZRp

A step toward advancing precision hormone therapies to reduce Alzheimer's risk

When it comes to post-menopausal hormone therapy, the type, route and duration all play a role in reducing the risk of neurodegenerative diseases.

from Women's Health News -- ScienceDaily https://ift.tt/3yRJZRp

The shape of nanoparticles in body fluids may help identify the type of cancer

A recent study has shown that the shape of cell-derived nanoparticles, known as 'extracellular vesicles' (EVs), in body fluids could be a biomarker for identifying types of cancer. In the study, scientists successfully measured the shape distributions of EVs derived from liver, breast, and colorectal cancer cells, showing that the shape distributions differ from one another.

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