First genetic risk factors identified for sudden unexplained death in children after age one

A new study, the largest of its kind to date, finds the first genetic causes of sudden unexplained death in children (SUDC).

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First genetic risk factors identified for sudden unexplained death in children after age one

A new study, the largest of its kind to date, finds the first genetic causes of sudden unexplained death in children (SUDC).

from Women's Health News -- ScienceDaily https://ift.tt/3pkgVjV

Overactive bladder and urinary incontinence worsen with age

If you're feeling more sudden urges to run to the bathroom as you age, you're not alone. A new study suggests postmenopausal women aged 45 to 54 years are more likely to have overactive bladder (OAB) syndrome. Additionally, obesity and multiple births put a woman at greater risk for stress urinary incontinence (SUI).

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Overactive bladder and urinary incontinence worsen with age

If you're feeling more sudden urges to run to the bathroom as you age, you're not alone. A new study suggests postmenopausal women aged 45 to 54 years are more likely to have overactive bladder (OAB) syndrome. Additionally, obesity and multiple births put a woman at greater risk for stress urinary incontinence (SUI).

from Women's Health News -- ScienceDaily https://ift.tt/323vdN2

Aging stiffens the blood vessels but their flexibility also fluctuates based on a woman’s hormone state

A study measured arterial stiffness in women from wide age range. Increased stiffness is an independent risk factor for cardiovascular disease. Age was a strong determinant of arterial stiffness. Indicative of the role of hormones, menstrual cycle phase, contraceptive pill phase and menopausal state were also associated with arterial stiffness.

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It takes more than one mutant copy of the PIK3CA gene to make breast cancer more aggressive, study finds

Breast cancers that have an overactive PI3K enzyme tend to be more aggressive and to spread and divide more like stem cells. But a new study uncovers a surprising relationship between PI3K activity and mutations in the PIK3CA gene that codes for the enzyme.

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It takes more than one mutant copy of the PIK3CA gene to make breast cancer more aggressive, study finds

Breast cancers that have an overactive PI3K enzyme tend to be more aggressive and to spread and divide more like stem cells. But a new study uncovers a surprising relationship between PI3K activity and mutations in the PIK3CA gene that codes for the enzyme.

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It takes more than one mutant copy of the PIK3CA gene to make breast cancer more aggressive, study finds

Breast cancers that have an overactive PI3K enzyme tend to be more aggressive and to spread and divide more like stem cells. But a new study uncovers a surprising relationship between PI3K activity and mutations in the PIK3CA gene that codes for the enzyme.

from Women's Health News -- ScienceDaily https://ift.tt/2YHfZLL

Function of mysterious structure found on neurons

Researchers have discovered that mysterious clusters of proteins found on neurons are calcium-signaling 'hotspots' that activate gene transcription, allowing neurons to produce crucial proteins. The discovery may help shape new research into the role of the hotspots in brain function and potentially lead to new classes of therapeutics.

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Function of mysterious structure found on neurons

Researchers have discovered that mysterious clusters of proteins found on neurons are calcium-signaling 'hotspots' that activate gene transcription, allowing neurons to produce crucial proteins. The discovery may help shape new research into the role of the hotspots in brain function and potentially lead to new classes of therapeutics.

from Women's Health News -- ScienceDaily https://ift.tt/31Ntmet

Plant-based gummy candy helps vegans and vegetarians get their vitamins

Worldwide, millions of people follow vegan and vegetarian diets for religious, ethical, environmental or economic reasons. While these diets have purported health benefits, they can also lack essential nutrients, such as vitamins B12 and D3, if not well-planned or supplemented correctly. Now, researchers have packed a strawberry-flavored gummy with these vitamins, formulating it without any animal products so vegans and vegetarians can reach their recommended daily allowances (RDA).

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Plant-based gummy candy helps vegans and vegetarians get their vitamins

Worldwide, millions of people follow vegan and vegetarian diets for religious, ethical, environmental or economic reasons. While these diets have purported health benefits, they can also lack essential nutrients, such as vitamins B12 and D3, if not well-planned or supplemented correctly. Now, researchers have packed a strawberry-flavored gummy with these vitamins, formulating it without any animal products so vegans and vegetarians can reach their recommended daily allowances (RDA).

from Women's Health News -- ScienceDaily https://ift.tt/3D6zAUy

Fat-secreted molecule lowers response to common cancer treatment

Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study.

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Fat-secreted molecule lowers response to common cancer treatment

Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study.

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Fat-secreted molecule lowers response to common cancer treatment

Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study.

from Women's Health News -- ScienceDaily https://ift.tt/306YvZs

For women, greater exposure to estrogen in life may protect brain regions that are vulnerable to Alzheimer’s

The drop in estrogen levels that occurs with menopause brings declines in the volumes of 'gray matter,' the cellular matter of the brain, in key brain regions that are also affected in Alzheimer's disease. But a new study suggests that greater cumulative exposure to estrogen in life, for example from having had more children or from having taken menopause hormone therapy, may counter this brain-shrinking effect.

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Nanoscale self-assembling salt-crystal ‘origami’ balls envelop liquids

Mechanical engineers have devised a technique of 'crystal capillary origami' where salt crystals spontaneously encapsulate liquid droplets. The process offers a new method of nanostructure encapsulation for applications in food industries, drug delivery and even medical devices.

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Nanoscale self-assembling salt-crystal ‘origami’ balls envelop liquids

Mechanical engineers have devised a technique of 'crystal capillary origami' where salt crystals spontaneously encapsulate liquid droplets. The process offers a new method of nanostructure encapsulation for applications in food industries, drug delivery and even medical devices.

from Women's Health News -- ScienceDaily https://ift.tt/3EO84LV

Researchers identify molecule that blocks immune cells from entering and killing breast tumors

Researchers have identified a key molecule in certain kinds of breast cancers that prevent immune cells from entering tumors and killing the cancer cells inside. This research could pave the way toward a new treatment for certain kinds of aggressive breast cancer.

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Chemo helps breast cancer cells get their ‘foot in the door’ to the lungs

A new study adds to the evidence that chemotherapy enhances cancer's spread beyond the primary tumor, showing how one chemo drug allows breast cancer cells to squeeze through and attach to blood vessel linings in the lungs.

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Sperm switch swimming patterns to locate egg

A new study reveals how sperm change their swimming patterns to navigate to the egg, shifting from a symmetrical motion that moves the sperm in a straight path to an asymmetrical one that promotes more circular swimming.

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Sperm switch swimming patterns to locate egg

A new study reveals how sperm change their swimming patterns to navigate to the egg, shifting from a symmetrical motion that moves the sperm in a straight path to an asymmetrical one that promotes more circular swimming.

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Gene signature identifies drivers of treatment resistance in metastatic breast cancer

A multi-institution team of researchers has discovered a genetic signature that can identify drivers of poor outcomes in advanced estrogen-receptor positive (ER+) breast cancer, which could one day lead to personalized treatment for patients.

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Gene signature identifies drivers of treatment resistance in metastatic breast cancer

A multi-institution team of researchers has discovered a genetic signature that can identify drivers of poor outcomes in advanced estrogen-receptor positive (ER+) breast cancer, which could one day lead to personalized treatment for patients.

from Breast Cancer News -- ScienceDaily https://ift.tt/2ZKdloZ

Gene signature identifies drivers of treatment resistance in metastatic breast cancer

A multi-institution team of researchers has discovered a genetic signature that can identify drivers of poor outcomes in advanced estrogen-receptor positive (ER+) breast cancer, which could one day lead to personalized treatment for patients.

from Women's Health News -- ScienceDaily https://ift.tt/2ZKdloZ

Bone mineral density decreases less than expected after menopause

Bone mineral density at the femoral neck bone in postmenopausal women decreased by an average of 10% during a 25-year follow-up, according to a new study. Being the world's hitherto longest follow-up of changes in bone mineral density in postmenopausal women, the study shows that bone loss after menopause is significantly lower than has previously been assumed on the basis of earlier studies.

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Bone mineral density decreases less than expected after menopause

Bone mineral density at the femoral neck bone in postmenopausal women decreased by an average of 10% during a 25-year follow-up, according to a new study. Being the world's hitherto longest follow-up of changes in bone mineral density in postmenopausal women, the study shows that bone loss after menopause is significantly lower than has previously been assumed on the basis of earlier studies.

from Women's Health News -- ScienceDaily https://www.sciencedaily.com/releases/2021/10/211027122047.htm

Metabolic memory plays a key role in breast cancer relapse

Molecular targets for therapies that could prevent breast cancer recurrence have been identified by a group of scientists who analyzed tumor cells that proved resistant to the original treatment. Recent advances in early detection and targeted therapy have led to a growing success in treating breast cancer upon first presentation. This often is achieved by silencing tumor driving oncogenes and causing tumor regression.

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Guidance on supplemental breast cancer screening for women with dense breast tissue

Researchers have made recommendations for clinicians and patients regarding supplemental screening for women with dense breast tissue.

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Guidance on supplemental breast cancer screening for women with dense breast tissue

Researchers have made recommendations for clinicians and patients regarding supplemental screening for women with dense breast tissue.

from Women's Health News -- ScienceDaily https://ift.tt/3m4sppW

Guidance on supplemental breast cancer screening for women with dense breast tissue

Researchers have made recommendations for clinicians and patients regarding supplemental screening for women with dense breast tissue.

from Women's Health News -- ScienceDaily https://ift.tt/3m4sppW

Starting mammography at age 40 would reduce disparities in deaths for Black women

If Black women begin mammography screening every other year starting at age 40, breast cancer deaths could be reduced by 57 percent compared to starting screening 10 years later according to recent analyses.

from Women's Health News -- ScienceDaily https://ift.tt/3DZTWPu

Starting mammography at age 40 would reduce disparities in deaths for Black women

If Black women begin mammography screening every other year starting at age 40, breast cancer deaths could be reduced by 57 percent compared to starting screening 10 years later according to recent analyses.

from Breast Cancer News -- ScienceDaily https://ift.tt/3DZTWPu

Starting mammography at age 40 would reduce disparities in deaths for Black women

If Black women begin mammography screening every other year starting at age 40, breast cancer deaths could be reduced by 57 percent compared to starting screening 10 years later according to recent analyses.

from Women's Health News -- ScienceDaily https://ift.tt/3DZTWPu

Scientists develop new sensor to capture calcium activity in cells

Researchers have developed a novel approach for detecting the activity of calcium within cells. The study demonstrates the effectiveness of a red biosensor that can directly monitor calcium at specific locations within a cell, a discovery that could aid in better understanding of the molecular basis of human diseases.

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Scientists develop new sensor to capture calcium activity in cells

Researchers have developed a novel approach for detecting the activity of calcium within cells. The study demonstrates the effectiveness of a red biosensor that can directly monitor calcium at specific locations within a cell, a discovery that could aid in better understanding of the molecular basis of human diseases.

from Women's Health News -- ScienceDaily https://ift.tt/3lYhH4p

Aging breast tissue could set the stage for invasive breast cancer

A new study examines how the extracellular matrix (ECM) -- an underlying network of molecules and proteins that provide the structure for tissue growth -- can trigger invasive cancer-related genes.

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Scientists map brain circuit that drives activity in fertile females

Scientists have known for a century that female animals become more active just as they are about to ovulate, a behavior that evolved to enhance their chances of mating when they are fertile.

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Scientists map brain circuit that drives activity in fertile females

Scientists have known for a century that female animals become more active just as they are about to ovulate, a behavior that evolved to enhance their chances of mating when they are fertile.

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Bone-loss discovery points to new treatment for osteoporosis

A new discovery about osteoporosis suggests a potential treatment target for that brittle-bone disease and for bone loss from rheumatoid arthritis.

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Bone-loss discovery points to new treatment for osteoporosis

A new discovery about osteoporosis suggests a potential treatment target for that brittle-bone disease and for bone loss from rheumatoid arthritis.

from Women's Health News -- ScienceDaily https://ift.tt/3FNo3eF

Data continues to show that American’s need at least 5 hours per week of physical activity to prevent some cancers

A new report finds more than 46,000 cancer cases annually in the United States could be prevented if Americans met the 5 hours per week of moderate-intensity recommended physical activity guidelines.

from Women's Health News -- ScienceDaily https://ift.tt/3BKgov9

Data continues to show that American’s need at least 5 hours per week of physical activity to prevent some cancers

A new report finds more than 46,000 cancer cases annually in the United States could be prevented if Americans met the 5 hours per week of moderate-intensity recommended physical activity guidelines.

from Breast Cancer News -- ScienceDaily https://ift.tt/3BKgov9

Data continues to show that American’s need at least 5 hours per week of physical activity to prevent some cancers

A new report finds more than 46,000 cancer cases annually in the United States could be prevented if Americans met the 5 hours per week of moderate-intensity recommended physical activity guidelines.

from Women's Health News -- ScienceDaily https://ift.tt/3BKgov9

Changes in menstrual cycle length before menopause may predict risk of heart disease

As women near menopause, their menstrual cycle length often becomes longer. The timing of these changes could provide clues about a person's risk of developing cardiovascular disease, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/3DCni6l

Changes in menstrual cycle length before menopause may predict risk of heart disease

As women near menopause, their menstrual cycle length often becomes longer. The timing of these changes could provide clues about a person's risk of developing cardiovascular disease, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/3DCni6l

Researchers find cervical cancer screening is overused – and underused as well

New research finds many women are screened too often for cervical cancer, leading to unnecessary procedures that may carry their own harms, while some women are not getting tested often enough, putting them at higher risk for poor outcomes.

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Researchers find cervical cancer screening is overused – and underused as well

New research finds many women are screened too often for cervical cancer, leading to unnecessary procedures that may carry their own harms, while some women are not getting tested often enough, putting them at higher risk for poor outcomes.

from Women's Health News -- ScienceDaily https://ift.tt/3FC5n1n

Breast milk of marijuana users does not hurt short-term health of early premature infants, long-term effects still unknown

Researchers compared early preterm infants who were fed breast milk from THC-positive mothers to those who were fed either formula or breast milk from THC-negative mothers and found no differences in short-term health impacts such as breathing difficulties, lung development, and feeding issues.

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Breast milk of marijuana users does not hurt short-term health of early premature infants, long-term effects still unknown

Researchers compared early preterm infants who were fed breast milk from THC-positive mothers to those who were fed either formula or breast milk from THC-negative mothers and found no differences in short-term health impacts such as breathing difficulties, lung development, and feeding issues.

from Women's Health News -- ScienceDaily https://ift.tt/3mH7HLZ

Cancer costs US more than $156 billion annually, with drugs a leading expense

Care for the 15 most prevalent types of cancer in the U.S. cost approximately $156.2 billion in 2018, according to a team researchers. The team also found that medication was the biggest expense and that medication expense for breast, lung, lymphoma and colorectal cancers incurred the most costs.

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Undiagnosed endometriosis compromises fertility treatment

Women with undiagnosed endometriosis will have difficulty falling pregnant without IVF, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/3a8hPHR

Undiagnosed endometriosis compromises fertility treatment

Women with undiagnosed endometriosis will have difficulty falling pregnant without IVF, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/3a8hPHR

New mouse model unlocks drug testing of hormone-sensitive human breast cancer

Scientists have created mice with a hormone profile that causes growth and metastatic spread of implanted human breast tumors. Results show that the team created a new mouse breed, called NSG-Pro, that produces levels of human prolactin similar to those in patients with metastatic estrogen receptor-positive breast cancer.

from Women's Health News -- ScienceDaily https://ift.tt/3FbKVnX

New mouse model unlocks drug testing of hormone-sensitive human breast cancer

Scientists have created mice with a hormone profile that causes growth and metastatic spread of implanted human breast tumors. Results show that the team created a new mouse breed, called NSG-Pro, that produces levels of human prolactin similar to those in patients with metastatic estrogen receptor-positive breast cancer.

from Women's Health News -- ScienceDaily https://ift.tt/3FbKVnX

New mouse model unlocks drug testing of hormone-sensitive human breast cancer

Scientists have created mice with a hormone profile that causes growth and metastatic spread of implanted human breast tumors. Results show that the team created a new mouse breed, called NSG-Pro, that produces levels of human prolactin similar to those in patients with metastatic estrogen receptor-positive breast cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/3FbKVnX

What you need to know about urinary tract infections

More than half of U.S. women will experience at least one urinary tract infection (UTI) in their lifetimes, while a quarter will have a subsequent infection. Recurrent urinary tract infections are defined as two or more infections in six months or three or more in a year.

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What you need to know about urinary tract infections

More than half of U.S. women will experience at least one urinary tract infection (UTI) in their lifetimes, while a quarter will have a subsequent infection. Recurrent urinary tract infections are defined as two or more infections in six months or three or more in a year.

from Women's Health News -- ScienceDaily https://ift.tt/3kZXjz4

Study shows hormone therapy not associated with an increased risk of developing dementia

New research shows that the use of menopausal hormone therapy (MHT -- also known as hormone replacement therapy, HRT) is not linked to an increased risk of developing dementia.

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Study shows hormone therapy not associated with an increased risk of developing dementia

New research shows that the use of menopausal hormone therapy (MHT -- also known as hormone replacement therapy, HRT) is not linked to an increased risk of developing dementia.

from Women's Health News -- ScienceDaily https://ift.tt/2Y6QvHD

Saliva testing may allow early detection of human papillomavirus–driven head and neck cancers

High-risk human papillomaviruses (HPV) can be detected at diagnosis in saliva samples from the vast majority of patients with HPV-driven head and neck cancers, improving disease identification and monitoring, according to a new study.

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Saliva testing may allow early detection of human papillomavirus–driven head and neck cancers

High-risk human papillomaviruses (HPV) can be detected at diagnosis in saliva samples from the vast majority of patients with HPV-driven head and neck cancers, improving disease identification and monitoring, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/2XVRSrQ

New approach to breast cancer prevention

Researchers suggest that advances in breast cancer prevention research have resulted in new and innovative opportunities to modify breast cancer risk and potentially reduce breast cancer incidence and mortality.

from Women's Health News -- ScienceDaily https://ift.tt/3kNooFD

New approach to breast cancer prevention

Researchers suggest that advances in breast cancer prevention research have resulted in new and innovative opportunities to modify breast cancer risk and potentially reduce breast cancer incidence and mortality.

from Breast Cancer News -- ScienceDaily https://ift.tt/3kNooFD

New approach to breast cancer prevention

Researchers suggest that advances in breast cancer prevention research have resulted in new and innovative opportunities to modify breast cancer risk and potentially reduce breast cancer incidence and mortality.

from Women's Health News -- ScienceDaily https://ift.tt/3kNooFD

An estrogen receptor that promotes cancer also causes drug resistance

Cancer cells proliferate despite a myriad of stresses -- from oxygen deprivation to chemotherapy -- that would kill any ordinary cell. Now, researchers have gained insight into how they may be doing this through the downstream activity of a powerful estrogen receptor. The discovery offers clues to overcoming resistance to therapies like tamoxifen that are used in many types of breast cancer.

from Women's Health News -- ScienceDaily https://ift.tt/3o3nhUA

An estrogen receptor that promotes cancer also causes drug resistance

Cancer cells proliferate despite a myriad of stresses -- from oxygen deprivation to chemotherapy -- that would kill any ordinary cell. Now, researchers have gained insight into how they may be doing this through the downstream activity of a powerful estrogen receptor. The discovery offers clues to overcoming resistance to therapies like tamoxifen that are used in many types of breast cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/3o3nhUA

An estrogen receptor that promotes cancer also causes drug resistance

Cancer cells proliferate despite a myriad of stresses -- from oxygen deprivation to chemotherapy -- that would kill any ordinary cell. Now, researchers have gained insight into how they may be doing this through the downstream activity of a powerful estrogen receptor. The discovery offers clues to overcoming resistance to therapies like tamoxifen that are used in many types of breast cancer.

from Women's Health News -- ScienceDaily https://ift.tt/3o3nhUA

Breast cancers: Ruptures in cell nuclei promotes tumor invasion

When cells multiply and migrate, they can be compressed and their nucleus may break open. This phenomenon causes DNA damage. Scientists have now shown that this facilitates the spread of cancer cells in breast tumors.

from Breast Cancer News -- ScienceDaily https://ift.tt/3u85M6z

Metastatic prostate cancer comes in two forms, which could guide treatment

Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment, information that could one day guide physicians in treating patients with the therapies best suited to their disease.

from Breast Cancer News -- ScienceDaily https://ift.tt/39MflPf

Different types of cancers are likely to spread to specific areas of the brain

Brain metastasis occurs when cancer in one part of the body spreads to the brain. The lifetime incidence of such metastatic brain tumors in cancer patients is between 20%-45%, research shows.

from Breast Cancer News -- ScienceDaily https://ift.tt/3nXB1jD

Studies biased toward genomes of people with European ancestry still predict cancer risk in diverse groups, research finds

Data sets that are biased by having too many genomes from people with European ancestry can still be applied to other ancestry groups to predict their risk of developing breast and prostate cancer, researchers report.

from Breast Cancer News -- ScienceDaily https://ift.tt/39c6WnA

Improving biomaterials design for bone regeneration

In a new study, researchers are investigating the types of material used in bone reconstruction to see which one works best.

from Women's Health News -- ScienceDaily https://ift.tt/3tMh67U

Improving biomaterials design for bone regeneration

In a new study, researchers are investigating the types of material used in bone reconstruction to see which one works best.

from Women's Health News -- ScienceDaily https://ift.tt/3tMh67U

Fountain of youth for aging stem cells in bone marrow

Epigenetic changes in old age increase risk of osteoporosis and bone fractures.

from Women's Health News -- ScienceDaily https://ift.tt/3tHD9gh

Fountain of youth for aging stem cells in bone marrow

Epigenetic changes in old age increase risk of osteoporosis and bone fractures.

from Women's Health News -- ScienceDaily https://ift.tt/3tHD9gh

Hormonal hazard: Chemicals used in paints and plastics can promote breast tumor growth

The increasing use of photoinitiators, especially in medical settings, has raised concerns about their adverse effects on human health. Now, scientists have shown that three photoinitiators -- 1-HCHPK, MBB, and MTMP -- show estrogen-like activity in mice and increase the growth of breast cancer tumors in these animals. Their results warn against the use of such chemicals in medical instruments like containers and call for the prompt development of safer alternatives.

from Women's Health News -- ScienceDaily https://ift.tt/3tGnHRg

Hormonal hazard: Chemicals used in paints and plastics can promote breast tumor growth

The increasing use of photoinitiators, especially in medical settings, has raised concerns about their adverse effects on human health. Now, scientists have shown that three photoinitiators -- 1-HCHPK, MBB, and MTMP -- show estrogen-like activity in mice and increase the growth of breast cancer tumors in these animals. Their results warn against the use of such chemicals in medical instruments like containers and call for the prompt development of safer alternatives.

from Breast Cancer News -- ScienceDaily https://ift.tt/3tGnHRg

Hormonal hazard: Chemicals used in paints and plastics can promote breast tumor growth

The increasing use of photoinitiators, especially in medical settings, has raised concerns about their adverse effects on human health. Now, scientists have shown that three photoinitiators -- 1-HCHPK, MBB, and MTMP -- show estrogen-like activity in mice and increase the growth of breast cancer tumors in these animals. Their results warn against the use of such chemicals in medical instruments like containers and call for the prompt development of safer alternatives.

from Women's Health News -- ScienceDaily https://ift.tt/3tGnHRg

One in two pregnancies are affected by iron deficiency, yet many women don’t get a simple screening test to check

Half of pregnant women who had a simple blood test to check their iron stores had low iron levels, and one in four had severe iron deficiency, according to a new article. But despite how common iron deficiency is, 40% of pregnant women in this large regional study never had their iron levels checked, and women of lower socioeconomic status were less likely to get tested. Researchers said the findings underscore the need to revisit clinical guidelines to ensure that ferritin testing, the standard measure of iron deficiency, is included as a routine part of maternal care and pregnancy health screenings.

from Women's Health News -- ScienceDaily https://ift.tt/3juCknC

One in two pregnancies are affected by iron deficiency, yet many women don’t get a simple screening test to check

Half of pregnant women who had a simple blood test to check their iron stores had low iron levels, and one in four had severe iron deficiency, according to a new article. But despite how common iron deficiency is, 40% of pregnant women in this large regional study never had their iron levels checked, and women of lower socioeconomic status were less likely to get tested. Researchers said the findings underscore the need to revisit clinical guidelines to ensure that ferritin testing, the standard measure of iron deficiency, is included as a routine part of maternal care and pregnancy health screenings.

from Women's Health News -- ScienceDaily https://ift.tt/3juCknC

No swimming? Molecule regulating sperm motility discovered

Researchers used protein sequence data analysis and genome editing technology to find that sperm protein SPATA33 plays an important role in sperm motility regulation. Their findings will aid in the development of male contraceptives and the investigation of the cause of male infertility.

from Women's Health News -- ScienceDaily https://ift.tt/3sU1Sh1

No swimming? Molecule regulating sperm motility discovered

Researchers used protein sequence data analysis and genome editing technology to find that sperm protein SPATA33 plays an important role in sperm motility regulation. Their findings will aid in the development of male contraceptives and the investigation of the cause of male infertility.

from Women's Health News -- ScienceDaily https://ift.tt/3sU1Sh1

High cholesterol fuels cancer by fostering resistance to a form of cell death

A research team has identified how breast cancer cells use cholesterol to develop tolerance to stress, making them impervious to death as they migrate from the original tumor site.

from Women's Health News -- ScienceDaily https://ift.tt/3guK4DW

High cholesterol fuels cancer by fostering resistance to a form of cell death

A research team has identified how breast cancer cells use cholesterol to develop tolerance to stress, making them impervious to death as they migrate from the original tumor site.

from Breast Cancer News -- ScienceDaily https://ift.tt/3guK4DW

High cholesterol fuels cancer by fostering resistance to a form of cell death

A research team has identified how breast cancer cells use cholesterol to develop tolerance to stress, making them impervious to death as they migrate from the original tumor site.

from Women's Health News -- ScienceDaily https://ift.tt/3guK4DW

Prediction models may reduce false-positives in MRI breast cancer screening

Prediction models based on clinical characteristics and imaging findings may help reduce the false-positive rate in women with dense breasts who undergo supplemental breast cancer screening with MRI, according to a new study.

from Breast Cancer News -- ScienceDaily https://ift.tt/2W7hb9R

Mechanisms of resistance to drug for triple-negative breast cancer identified

Triple-negative breast cancer cells exposed to the antibody-drug conjugate sacituzumab govitecan may develop resistance to this powerful drug through alterations in both the target of the antibody and the target of the toxic payload. The findings illustrate how uncovering such mechanisms will critically inform strategies to overcome resistance to sacituzumab govitecan.

from Breast Cancer News -- ScienceDaily https://ift.tt/3mg7DE7

Prediction models may reduce false-positives in MRI breast cancer screening

Prediction models based on clinical characteristics and imaging findings may help reduce the false-positive rate in women with dense breasts who undergo supplemental breast cancer screening with MRI, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/2W7hb9R

Mechanisms of resistance to drug for triple-negative breast cancer identified

Triple-negative breast cancer cells exposed to the antibody-drug conjugate sacituzumab govitecan may develop resistance to this powerful drug through alterations in both the target of the antibody and the target of the toxic payload. The findings illustrate how uncovering such mechanisms will critically inform strategies to overcome resistance to sacituzumab govitecan.

from Women's Health News -- ScienceDaily https://ift.tt/3mg7DE7

Prediction models may reduce false-positives in MRI breast cancer screening

Prediction models based on clinical characteristics and imaging findings may help reduce the false-positive rate in women with dense breasts who undergo supplemental breast cancer screening with MRI, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/2W7hb9R

Mechanisms of resistance to drug for triple-negative breast cancer identified

Triple-negative breast cancer cells exposed to the antibody-drug conjugate sacituzumab govitecan may develop resistance to this powerful drug through alterations in both the target of the antibody and the target of the toxic payload. The findings illustrate how uncovering such mechanisms will critically inform strategies to overcome resistance to sacituzumab govitecan.

from Women's Health News -- ScienceDaily https://ift.tt/3mg7DE7

Researchers pinpoint how PARP inhibitors combat BRCA1 and BRCA2 tumor cells

PARP inhibitors, used to treat patients with cancer of the breast, ovaries, prostate and pancreas, work by inducing persistent DNA gaps in tumor cells with BRCA1 and BRCA2 mutations. The discovery offers the potential to monitor tumors for the development of resistance to PARP inhibitor therapy, and to identify drug combinations that could prevent drug resistance and improve the efficacy of cancer therapies.

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Atomic nuclei and leptons: Milestone in the calculation of cross sections

A team has succeeded in computing how atomic nuclei of the Calcium element behave in collisions with electrons. Results agree very well with available experimental data. For the first time, a calculation based on a fundamental theory is capable of correctly describing experiments for a nucleus as heavy as Calcium. Of particular relevance is the potential that such calculations could have in the future to interpret neutrino experiments.

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Atomic nuclei and leptons: Milestone in the calculation of cross sections

A team has succeeded in computing how atomic nuclei of the Calcium element behave in collisions with electrons. Results agree very well with available experimental data. For the first time, a calculation based on a fundamental theory is capable of correctly describing experiments for a nucleus as heavy as Calcium. Of particular relevance is the potential that such calculations could have in the future to interpret neutrino experiments.

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Breakthrough in understanding genesis of fibroids

Scientists have made a breakthrough in understanding the genesis of uterine leiomyomas, also called fibroids.

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Breakthrough in understanding genesis of fibroids

Scientists have made a breakthrough in understanding the genesis of uterine leiomyomas, also called fibroids.

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New genes linked to longer reproductive lifespan in women

Scientists have identified nearly 300 gene variations that influence reproductive lifespan in women. Additionally, in mice, they have successfully manipulated several key genes associated with these variants to extend their reproductive lifespan. Their findings substantially increase our knowledge of the reproductive ageing process, as well as providing ways to improve the prediction of which women might reach menopause earlier than others.

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New genes linked to longer reproductive lifespan in women

Scientists have identified nearly 300 gene variations that influence reproductive lifespan in women. Additionally, in mice, they have successfully manipulated several key genes associated with these variants to extend their reproductive lifespan. Their findings substantially increase our knowledge of the reproductive ageing process, as well as providing ways to improve the prediction of which women might reach menopause earlier than others.

from Women's Health News -- ScienceDaily https://ift.tt/3rTFOm0

Statins may improve survival for triple-negative breast cancer patients

A new study found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy to access and produce minimal side effects, this could have an important impact on outcomes for this aggressive disease.

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Statins may improve survival for triple-negative breast cancer patients

A new study found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy to access and produce minimal side effects, this could have an important impact on outcomes for this aggressive disease.

from Breast Cancer News -- ScienceDaily https://ift.tt/2WHKsrG

Statins may improve survival for triple-negative breast cancer patients

A new study found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy to access and produce minimal side effects, this could have an important impact on outcomes for this aggressive disease.

from Women's Health News -- ScienceDaily https://ift.tt/2WHKsrG

New relevant target for PARP inhibitor talazoparib

Researchers report the identification of a new target for the PARP inhibitor drug talazoparib and show that combination treatment with talazoparib and the WEE1 inhibitor adavosertib results in enhanced anti-cancer effects.

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Heart cell protein could lead to new treatments for heart failure and recovery

A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, according to a new study.

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Heart cell protein could lead to new treatments for heart failure and recovery

A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, according to a new study.

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Seeking a unique treatment for lobular breast cancer

In an attempt to find out why the long-term outcomes are poorer for patients with lobular breast cancer -- which affects some 40,000 women a year -- researchers began looking at the role of the protein MDC1 in tumor cells.

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Postmenopausal women can dance their way to better health

Women often struggle with managing their weight and other health risk factors, such as high cholesterol, once they transition through menopause. A new study suggests that dancing may effectively lower cholesterol levels, improve fitness and body composition and in the process, improve self-esteem.

from Women's Health News -- ScienceDaily https://ift.tt/2WviSxU

Seeking a unique treatment for lobular breast cancer

In an attempt to find out why the long-term outcomes are poorer for patients with lobular breast cancer -- which affects some 40,000 women a year -- researchers began looking at the role of the protein MDC1 in tumor cells.

from Women's Health News -- ScienceDaily https://ift.tt/2V2xWCy

Postmenopausal women can dance their way to better health

Women often struggle with managing their weight and other health risk factors, such as high cholesterol, once they transition through menopause. A new study suggests that dancing may effectively lower cholesterol levels, improve fitness and body composition and in the process, improve self-esteem.

from Women's Health News -- ScienceDaily https://ift.tt/2WviSxU

Seeking a unique treatment for lobular breast cancer

In an attempt to find out why the long-term outcomes are poorer for patients with lobular breast cancer -- which affects some 40,000 women a year -- researchers began looking at the role of the protein MDC1 in tumor cells.

from Breast Cancer News -- ScienceDaily https://ift.tt/2V2xWCy

New approach eradicates breast cancer in mice

A new approach to treating breast cancer kills 95 to 100 percent of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels.

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New approach eradicates breast cancer in mice

A new approach to treating breast cancer kills 95 to 100 percent of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels.

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New approach eradicates breast cancer in mice

A new approach to treating breast cancer kills 95 to 100 percent of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels.

from Women's Health News -- ScienceDaily https://ift.tt/3y4EA9O

Study finds calcium precisely directs blood flow in the brain

Researchers have shown how the brain communicates to blood vessels when in need of energy, and how these blood vessels respond by relaxing or constricting to direct blood flow to specific brain regions.

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Study finds calcium precisely directs blood flow in the brain

Researchers have shown how the brain communicates to blood vessels when in need of energy, and how these blood vessels respond by relaxing or constricting to direct blood flow to specific brain regions.

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Cognitive decline may help predict future fracture risk in women

A 16-year study has revealed a link between cognitive decline, bone loss and fracture risk in women.

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Cognitive decline may help predict future fracture risk in women

A 16-year study has revealed a link between cognitive decline, bone loss and fracture risk in women.

from Women's Health News -- ScienceDaily https://ift.tt/3iB4WcP

Unleashing Treg cells may lead to treatments for multiple sclerosis

In a new study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

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Unleashing Treg cells may lead to treatments for multiple sclerosis

In a new study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

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Mechanisms to separately regulate synaptic vesicle release and recycling

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses.

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Mechanisms to separately regulate synaptic vesicle release and recycling

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses.

from Women's Health News -- ScienceDaily https://ift.tt/3xQbmex

New study links moderate alcohol use with higher cancer risk

A new study has found an association between alcohol and a substantially higher risk of several forms of cancer, including breast, colon, and oral cancers. Increased risk was evident even among light to moderate drinkers (up to two drinks a day), who represented 1 in 7 of all new cancers in 2020 and more than 100,000 cases worldwide.

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A step toward advancing precision hormone therapies to reduce Alzheimer's risk

When it comes to post-menopausal hormone therapy, the type, route and duration all play a role in reducing the risk of neurodegenerative diseases.

from Women's Health News -- ScienceDaily https://ift.tt/3yRJZRp

A step toward advancing precision hormone therapies to reduce Alzheimer's risk

When it comes to post-menopausal hormone therapy, the type, route and duration all play a role in reducing the risk of neurodegenerative diseases.

from Women's Health News -- ScienceDaily https://ift.tt/3yRJZRp

The shape of nanoparticles in body fluids may help identify the type of cancer

A recent study has shown that the shape of cell-derived nanoparticles, known as 'extracellular vesicles' (EVs), in body fluids could be a biomarker for identifying types of cancer. In the study, scientists successfully measured the shape distributions of EVs derived from liver, breast, and colorectal cancer cells, showing that the shape distributions differ from one another.

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GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

GluN3A-deficient mice display all aspects of Alzheimer's neurodegeneration.

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GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

GluN3A-deficient mice display all aspects of Alzheimer's neurodegeneration.

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Drug doubles down on bone cancer, metastasis

Researchers develop an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits metastasis.

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Drug doubles down on bone cancer, metastasis

Researchers develop an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits metastasis.

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Drug doubles down on bone cancer, metastasis

Researchers develop an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits metastasis.

from Women's Health News -- ScienceDaily https://ift.tt/3daspzI

Fertility drugs do not increase breast cancer risk, study finds

Drugs routinely used during fertility treatments to release eggs do not increase the risk of developing breast cancer, new research has shown.

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Fertility drugs do not increase breast cancer risk, study finds

Drugs routinely used during fertility treatments to release eggs do not increase the risk of developing breast cancer, new research has shown.

from Women's Health News -- ScienceDaily https://ift.tt/3xJT8uN

Fertility drugs do not increase breast cancer risk, study finds

Drugs routinely used during fertility treatments to release eggs do not increase the risk of developing breast cancer, new research has shown.

from Women's Health News -- ScienceDaily https://ift.tt/3xJT8uN

Some blood pressure-lowering meds linked to less memory decline in older adults, study finds

High blood pressure is a risk factor for cognitive decline and dementia in older adults. Studies have shown that commonly prescribed high blood pressure medications, or antihypertensives, may have a positive, beneficial impact on cognitive function including memory. This meta-analysis compares the impact on memory over time associated with taking antihypertensives that cross the blood-brain barrier versus those that do not.

from Women's Health News -- ScienceDaily https://ift.tt/3wM4xuc

Some blood pressure-lowering meds linked to less memory decline in older adults, study finds

High blood pressure is a risk factor for cognitive decline and dementia in older adults. Studies have shown that commonly prescribed high blood pressure medications, or antihypertensives, may have a positive, beneficial impact on cognitive function including memory. This meta-analysis compares the impact on memory over time associated with taking antihypertensives that cross the blood-brain barrier versus those that do not.

from Women's Health News -- ScienceDaily https://ift.tt/3wM4xuc

Does zinc inhibit or promote growth of kidney stones? Well, both

In the first study to validate conflicting theories, a researcher has confirmed that the zinc actually does inhibit and promote the growth of kidney stones at the same time.

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Does zinc inhibit or promote growth of kidney stones? Well, both

In the first study to validate conflicting theories, a researcher has confirmed that the zinc actually does inhibit and promote the growth of kidney stones at the same time.

from Women's Health News -- ScienceDaily https://ift.tt/3cGmPVH

Cholesterol metabolite induces production of cancer-promoting vesicles

Scientists studying the link between cholesterol and breast cancer report that a byproduct of cholesterol metabolism causes some cells to send out cancer-promoting signals to other cells. These signals are packaged in membrane-bound compartments called extracellular vesicles.

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New findings offer improved therapy of early-stage, BRCA mutation-associated breast cancer

A new treatment has potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer. These results represent the first time a PARP inhibitor has been shown to significantly reduce the risk of breast cancer returning in high-risk patients following completion of standard chemotherapy, surgery and radiation therapy.

from Breast Cancer News -- ScienceDaily https://ift.tt/2Rp5PvL

Longstanding fallopian tube transport debate solved

Yan research group has solved a longstanding scientific debate about the mechanism underlying the gamete and embryo transport within the Fallopian tube. Using a mouse model where the animals lacked motile cilia in the oviduct, they demonstrated that motile cilia in the very distal end of the Fallopian tube, the infundibulum, are essential for oocyte pickup.

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Longstanding fallopian tube transport debate solved

Yan research group has solved a longstanding scientific debate about the mechanism underlying the gamete and embryo transport within the Fallopian tube. Using a mouse model where the animals lacked motile cilia in the oviduct, they demonstrated that motile cilia in the very distal end of the Fallopian tube, the infundibulum, are essential for oocyte pickup.

from Women's Health News -- ScienceDaily https://ift.tt/3vsiZa5

With a kitchen freezer and plant cellulose, an aerogel for therapeutic use is developed

A new low-cost and sustainable technique would boost the possibilities for hospitals and clinics to deliver therapeutics with aerogels, a foam-like material now found in such high-tech applications as insulation for spacesuits and breathable plasters.

from Women's Health News -- ScienceDaily https://ift.tt/2RCe5J0

With a kitchen freezer and plant cellulose, an aerogel for therapeutic use is developed

A new low-cost and sustainable technique would boost the possibilities for hospitals and clinics to deliver therapeutics with aerogels, a foam-like material now found in such high-tech applications as insulation for spacesuits and breathable plasters.

from Women's Health News -- ScienceDaily https://ift.tt/2RCe5J0

Study finds women with osteoporosis and low bone density are at increased risk of hearing loss

Researchers found that risk of subsequent moderate or worse hearing loss was up to 40 percent higher in study participants with osteoporosis or LBD.

from Women's Health News -- ScienceDaily https://ift.tt/34g1CNz

Study finds women with osteoporosis and low bone density are at increased risk of hearing loss

Researchers found that risk of subsequent moderate or worse hearing loss was up to 40 percent higher in study participants with osteoporosis or LBD.

from Women's Health News -- ScienceDaily https://ift.tt/34g1CNz

New insights into androgen's action could boost battle against prostate cancer

Researchers have unveiled important new insights into how hormones known as androgens act on our cells - and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.

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New study shows flies mutant for schizophrenia-associated genes respond well to anti-psychotics

Scientists have successfully treated flies displaying behavioral problems linked to newly discovered schizophrenia-associated genes in humans, using common anti-psychotics.

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New study shows flies mutant for schizophrenia-associated genes respond well to anti-psychotics

Scientists have successfully treated flies displaying behavioral problems linked to newly discovered schizophrenia-associated genes in humans, using common anti-psychotics.

from Women's Health News -- ScienceDaily https://ift.tt/3v347i6

Low-dose, four-drug combo blocks cancer spread in mice

Low doses of a four-drug combination helps prevent the spread of cancer in mice without triggering drug resistance or recurrence, shows a new study.

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Vegetarians have healthier levels of disease markers than meat-eaters

Vegetarians appear to have a healthier biomarker profile than meat-eaters, and this applies to adults of any age and weight, and is also unaffected by smoking and alcohol consumption, according to a new study in over 166,000 UK adults.

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Vegetarians have healthier levels of disease markers than meat-eaters

Vegetarians appear to have a healthier biomarker profile than meat-eaters, and this applies to adults of any age and weight, and is also unaffected by smoking and alcohol consumption, according to a new study in over 166,000 UK adults.

from Women's Health News -- ScienceDaily https://ift.tt/2SIcrWj

Thin and brittle bones strongly linked to women's heart disease risk

Thin and brittle bones are strongly linked to women's heart disease risk, with thinning of the lower (lumbar) spine, top of the thigh bone (femoral neck), and hip especially predictive of a heightened heart attack and stroke risk.

from Women's Health News -- ScienceDaily https://ift.tt/3vIVqJQ

Thin and brittle bones strongly linked to women's heart disease risk

Thin and brittle bones are strongly linked to women's heart disease risk, with thinning of the lower (lumbar) spine, top of the thigh bone (femoral neck), and hip especially predictive of a heightened heart attack and stroke risk.

from Women's Health News -- ScienceDaily https://ift.tt/3vIVqJQ

One bone fracture increases risk for subsequent breaks in postmenopausal women

Current guidelines for managing osteoporosis specifically call out hip or spine fractures for increasing the risk for subsequent bone breaks. But a new study suggests that fractures in the arm, wrist, leg and other parts of the body should also set off alarm bells. A fracture, no matter the location, indicates a general tendency to break a bone in the future at a different location.

from Women's Health News -- ScienceDaily https://ift.tt/33jdYUD

One bone fracture increases risk for subsequent breaks in postmenopausal women

Current guidelines for managing osteoporosis specifically call out hip or spine fractures for increasing the risk for subsequent bone breaks. But a new study suggests that fractures in the arm, wrist, leg and other parts of the body should also set off alarm bells. A fracture, no matter the location, indicates a general tendency to break a bone in the future at a different location.

from Women's Health News -- ScienceDaily https://ift.tt/33jdYUD

Few young adult men have gotten the HPV vaccine

Using data from the 2010-2018 National Health Interview Surveys, researchers found that just 16% of men who were 18 to 21 years old had received at least one dose of the HPV vaccine at any age. In comparison, 42% of women in the same age bracket had gotten at least one shot of the vaccine.

from Women's Health News -- ScienceDaily https://ift.tt/2PsmoWF

Few young adult men have gotten the HPV vaccine

Using data from the 2010-2018 National Health Interview Surveys, researchers found that just 16% of men who were 18 to 21 years old had received at least one dose of the HPV vaccine at any age. In comparison, 42% of women in the same age bracket had gotten at least one shot of the vaccine.

from Women's Health News -- ScienceDaily https://ift.tt/2PsmoWF

Higher mushroom consumption is associated with a lower risk of cancer

Higher mushroom consumption is associated with a lower risk of cancer, according to a new study. The systematic review and meta-analysis examined 17 cancer studies published from 1966 to 2020. Analyzing data from more than 19,500 cancer patients, researchers explored the relationship between mushroom consumption and cancer risk.

from Breast Cancer News -- ScienceDaily https://ift.tt/2Pdq2U6

Review summarizes known links between endocrine disruptors and breast cancer risk

Exposure to certain endocrine-disrupting chemicals could elevate the risk of breast cancer, according to a new comprehensive systematic review of epidemiological research. However, for many chemicals, evidence is inconsistent or still limited.

from Breast Cancer News -- ScienceDaily https://ift.tt/3tBYHtP

Review summarizes known links between endocrine disruptors and breast cancer risk

Exposure to certain endocrine-disrupting chemicals could elevate the risk of breast cancer, according to a new comprehensive systematic review of epidemiological research. However, for many chemicals, evidence is inconsistent or still limited.

from Women's Health News -- ScienceDaily https://ift.tt/3tBYHtP

Review summarizes known links between endocrine disruptors and breast cancer risk

Exposure to certain endocrine-disrupting chemicals could elevate the risk of breast cancer, according to a new comprehensive systematic review of epidemiological research. However, for many chemicals, evidence is inconsistent or still limited.

from Women's Health News -- ScienceDaily https://ift.tt/3tBYHtP

Leaking calcium in neurons an early sign of Alzheimer's pathology

Alzheimer's disease is known for its slow attack on neurons crucial to memory and cognition. But why are these particular neurons in aging brains so susceptible to the disease's ravages, while others remain resilient?

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Leaking calcium in neurons an early sign of Alzheimer's pathology

Alzheimer's disease is known for its slow attack on neurons crucial to memory and cognition. But why are these particular neurons in aging brains so susceptible to the disease's ravages, while others remain resilient?

from Women's Health News -- ScienceDaily https://ift.tt/3a3gQc3

Blocking a protein could help overcome cancer resistance to PARP inhibitors

Researchers have found that blocking a specific protein could increase tumor sensitivity to treatment with PARP inhibitors. Their work suggests combining treatments could lead to improved therapy for patients with inheritable breast cancers.

from Breast Cancer News -- ScienceDaily https://ift.tt/3fY9IkX

Experimental treatment offers hope of fertility for early menopausal women

Menopause typically signals the end of a woman's ability to become pregnant. However, in a small new study, a novel approach of administering platelet-rich plasma and gonadotropins near the ovarian follicles is showing promise in restoring ovarian function.

from Women's Health News -- ScienceDaily https://ift.tt/3ftcTkw

Experimental treatment offers hope of fertility for early menopausal women

Menopause typically signals the end of a woman's ability to become pregnant. However, in a small new study, a novel approach of administering platelet-rich plasma and gonadotropins near the ovarian follicles is showing promise in restoring ovarian function.

from Women's Health News -- ScienceDaily https://ift.tt/3ftcTkw

Protein rewires metabolism to block cancer cell death, may allow cancer spread

One specific protein may be a master regulator for changing how cancer cells consume nutrients from their environments, preventing cell death and increasing the likelihood the cancer could spread, a study has shown.

from Breast Cancer News -- ScienceDaily https://ift.tt/3sDSBZw

Plants remember drought

During drought, plants use a signalling molecule known from animals to limit their water loss. The molecule provides them with a kind of memory of how dry the day was.

from Women's Health News -- ScienceDaily https://ift.tt/2PgIong

Plants remember drought

During drought, plants use a signalling molecule known from animals to limit their water loss. The molecule provides them with a kind of memory of how dry the day was.

from Women's Health News -- ScienceDaily https://ift.tt/2PgIong

High vitamin D levels may protect against COVID-19, especially for Black people, study suggests

In a retrospective study of individuals tested for COVID-19, vitamin D levels above those traditionally considered sufficient were associated with a lower risk of COVID-19.

from Women's Health News -- ScienceDaily https://ift.tt/393T0wA

High vitamin D levels may protect against COVID-19, especially for Black people, study suggests

In a retrospective study of individuals tested for COVID-19, vitamin D levels above those traditionally considered sufficient were associated with a lower risk of COVID-19.

from Women's Health News -- ScienceDaily https://ift.tt/393T0wA

Exposure to common chemical during pregnancy may reduce protection against breast cancer

Low doses of propylparaben - a chemical preservative found in food, drugs and cosmetics - can alter pregnancy-related changes in the breast in ways that may lessen the protection against breast cancer that pregnancy hormones normally convey, according to new research.

from Breast Cancer News -- ScienceDaily https://ift.tt/3132WSl

Exposure to common chemical during pregnancy may reduce protection against breast cancer

Low doses of propylparaben - a chemical preservative found in food, drugs and cosmetics - can alter pregnancy-related changes in the breast in ways that may lessen the protection against breast cancer that pregnancy hormones normally convey, according to new research.

from Women's Health News -- ScienceDaily https://ift.tt/3132WSl

Exposure to common chemical during pregnancy may reduce protection against breast cancer

Low doses of propylparaben - a chemical preservative found in food, drugs and cosmetics - can alter pregnancy-related changes in the breast in ways that may lessen the protection against breast cancer that pregnancy hormones normally convey, according to new research.

from Women's Health News -- ScienceDaily https://ift.tt/3132WSl

New research shows marijuana THC stays in breast milk for six weeks

Researchers have found that tetrahydrocannabinol (THC), the psychoactive component of marijuana, stays in breast milk for up to six weeks, further supporting the recommendations to abstain from marijuana use during pregnancy and while a mother is breastfeeding.

from Women's Health News -- ScienceDaily https://ift.tt/3qKZ5UH

New research shows marijuana THC stays in breast milk for six weeks

Researchers have found that tetrahydrocannabinol (THC), the psychoactive component of marijuana, stays in breast milk for up to six weeks, further supporting the recommendations to abstain from marijuana use during pregnancy and while a mother is breastfeeding.

from Women's Health News -- ScienceDaily https://ift.tt/3qKZ5UH

Breast cancer: The risks of brominated flame retardants

Brominated flame retardants may lead to early mammary gland development, which is linked to an increased risk of breast cancer.

from Women's Health News -- ScienceDaily https://ift.tt/2PX7wzs

Breast cancer: The risks of brominated flame retardants

Brominated flame retardants may lead to early mammary gland development, which is linked to an increased risk of breast cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/2PX7wzs

Breast cancer: The risks of brominated flame retardants

Brominated flame retardants may lead to early mammary gland development, which is linked to an increased risk of breast cancer.

from Women's Health News -- ScienceDaily https://ift.tt/2PX7wzs

Accelerating gains in abdominal fat during menopause tied to heart disease risk

Women who experience an accelerated accumulation of abdominal fat during menopause are at greater risk of heart disease, even if their weight stays steady, according to a new analysis. The study -- based on a quarter century of data collected on hundreds of women -- indicates that measuring waist circumference during preventive health care appointments for midlife women could be a better early indicator of heart disease risk than weight or BMI.

from Women's Health News -- ScienceDaily https://ift.tt/3v0CoPJ

Accelerating gains in abdominal fat during menopause tied to heart disease risk

Women who experience an accelerated accumulation of abdominal fat during menopause are at greater risk of heart disease, even if their weight stays steady, according to a new analysis. The study -- based on a quarter century of data collected on hundreds of women -- indicates that measuring waist circumference during preventive health care appointments for midlife women could be a better early indicator of heart disease risk than weight or BMI.

from Women's Health News -- ScienceDaily https://ift.tt/3v0CoPJ

4D bioengineering materials bend, curve like natural tissue

Researchers have developed new 4D hydrogels -- 3D materials that have the ability to change shape over time in response to stimuli -- that can morph multiple times in a preprogrammed or on-demand manner in response to external trigger signals.

from Women's Health News -- ScienceDaily https://ift.tt/2Oe0024

4D bioengineering materials bend, curve like natural tissue

Researchers have developed new 4D hydrogels -- 3D materials that have the ability to change shape over time in response to stimuli -- that can morph multiple times in a preprogrammed or on-demand manner in response to external trigger signals.

from Women's Health News -- ScienceDaily https://ift.tt/2Oe0024

What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID

When women undergo breast imaging shortly after receiving a COVID-19 vaccine in the arm, their tests may show swollen lymph nodes in the armpit area. Radiologists say that this is usually a normal finding, and if there are no other concerns, no additional imaging tests are needed unless the lymph nodes remain swollen for more than six weeks after vaccination. The team has published an approach to help avoid delays in both vaccinations and breast cancer screening.

from Breast Cancer News -- ScienceDaily https://ift.tt/3aYJCf4

Proton therapy induces biologic response to attack treatment-resistant cancers

Researchers have developed a novel proton therapy technique to more specifically target cancer cells that resist other forms of treatment. The technique is called LEAP, an acronym for 'biologically enhanced particle therapy.'

from Breast Cancer News -- ScienceDaily https://ift.tt/3s4DK9O

Radioactive bone cement may be safer in treating spinal tumors

A radioactive bone cement that's injected into bone to provide support and local irradiation is proving to be a safer alternative to conventional radiation therapy for bone tumors, according to a new study.

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Radioactive bone cement may be safer in treating spinal tumors

A radioactive bone cement that's injected into bone to provide support and local irradiation is proving to be a safer alternative to conventional radiation therapy for bone tumors, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/2NdBuy3

Drug is promising against pancreatic and breast cancers

The drug is effective at treating pancreatic cancer and prolonging survival in mice, according to a new study. A second study shows the drug is also effective against triple-negative breast cancer, a fast-growing and hard-to-treat type of breast cancer that carries a poor prognosis. Clinical trials are set to begin in 2021.

from Breast Cancer News -- ScienceDaily visit

A 'skeletal age' calculator to predict bone fracture risk

Researchers have developed a model to predict the biological age of bones that may improve the management of osteoporotic fractures.

from Women's Health News -- ScienceDaily https://ift.tt/3a1Kuir

Halt cell recycling to treat cancer

Targeting and changing autophagy, otherwise known as cell recycling, has been linked to helping control or diminish certain cancers. Now, researchers have shown that completely halting this process in a very aggressive form of breast cancer may improve outcomes for patients one day.

from Breast Cancer News -- ScienceDaily https://ift.tt/2MBXXVn

Study links exposure to nighttime artificial lights with elevated thyroid cancer risk

People living in regions with high levels of outdoor artificial light at night may face a higher risk of developing thyroid cancer.

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Study links exposure to nighttime artificial lights with elevated thyroid cancer risk

People living in regions with high levels of outdoor artificial light at night may face a higher risk of developing thyroid cancer.

from Women's Health News -- ScienceDaily https://ift.tt/3rwMlSf

Study links exposure to nighttime artificial lights with elevated thyroid cancer risk

People living in regions with high levels of outdoor artificial light at night may face a higher risk of developing thyroid cancer.

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Working outdoors linked to lower risk of breast cancer among older women

Working outdoors over many years is linked to a lower risk of breast cancer in women after the age of 50, finds new research.

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Working outdoors linked to lower risk of breast cancer among older women

Working outdoors over many years is linked to a lower risk of breast cancer in women after the age of 50, finds new research.

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Working outdoors linked to lower risk of breast cancer among older women

Working outdoors over many years is linked to a lower risk of breast cancer in women after the age of 50, finds new research.

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Imaging identifies breast cancer patients unlikely to benefit from hormone therapy

Hormone therapy can be very effective for so-called estrogen receptor-positive breast cancer. But it only works for a little more than half of women who receive the treatment. In a small study, researchers found that women whose tumors did not respond to a one-day estrogen challenge did not benefit from hormone therapy. The findings could help doctors choose treatments most likely to help their patients.

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Imaging identifies breast cancer patients unlikely to benefit from hormone therapy

Hormone therapy can be very effective for so-called estrogen receptor-positive breast cancer. But it only works for a little more than half of women who receive the treatment. In a small study, researchers found that women whose tumors did not respond to a one-day estrogen challenge did not benefit from hormone therapy. The findings could help doctors choose treatments most likely to help their patients.

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How breast cancer cells hide from immune attack

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified how breast cancer cells hide from immune cells to stay alive. The discovery could lead to better immunotherapy treatment for patients.

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How breast cancer cells hide from immune attack

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified how breast cancer cells hide from immune cells to stay alive. The discovery could lead to better immunotherapy treatment for patients.

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How breast cancer cells hide from immune attack

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified how breast cancer cells hide from immune cells to stay alive. The discovery could lead to better immunotherapy treatment for patients.

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Researchers develop technique to replicate bone-remodeling processes

A multidisciplinary research team has developed a technique to replicate bone tissue complexity and bone-remodeling processes. This breakthrough could help researchers further their study of bone biology and assist in improving development of drugs for osteoporosis.

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Researchers develop technique to replicate bone-remodeling processes

A multidisciplinary research team has developed a technique to replicate bone tissue complexity and bone-remodeling processes. This breakthrough could help researchers further their study of bone biology and assist in improving development of drugs for osteoporosis.

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Hypertension symptoms in women often mistaken for menopause

Pregnancy complications and early menopause increase women's future risk of heart disease. Cardiologists, gynaecologists and endocrinologists recommend how to help middle-aged women prevent later heart problems.

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Hypertension symptoms in women often mistaken for menopause

Pregnancy complications and early menopause increase women's future risk of heart disease. Cardiologists, gynaecologists and endocrinologists recommend how to help middle-aged women prevent later heart problems.

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When -- not what -- obese mice ate reduced breast cancer risk

Researchers report that intermittent fasting reduced breast cancer risk in obese mice.

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When -- not what -- obese mice ate reduced breast cancer risk

Researchers report that intermittent fasting reduced breast cancer risk in obese mice.

from Women's Health News -- ScienceDaily https://ift.tt/3a8o5Pk

When -- not what -- obese mice ate reduced breast cancer risk

Researchers report that intermittent fasting reduced breast cancer risk in obese mice.

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Scientists use a novel ink to 3D print 'bone' with living cells

3D printers may one day become a permanent fixture of the operating theatre after scientists showed they could print bone-like structures containing living cells.

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Scientists use a novel ink to 3D print 'bone' with living cells

3D printers may one day become a permanent fixture of the operating theatre after scientists showed they could print bone-like structures containing living cells.

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Better post-surgery care would dramatically improve cancer survival

Patients' chances of survival after cancer surgery is strongly linked with the standard of post-operation hospital care, a major international study suggests.

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Scientists discover link between nicotine and breast cancer metastasis

Scientists have found that nicotine promotes the spread of breast cancer cells into the lungs.

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Scientists discover link between nicotine and breast cancer metastasis

Scientists have found that nicotine promotes the spread of breast cancer cells into the lungs.

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Scientists discover link between nicotine and breast cancer metastasis

Scientists have found that nicotine promotes the spread of breast cancer cells into the lungs.

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Researchers identify how cancer cells adapt to survive harsh tumor microenvironments

To better understand the conditions that select for the Warburg Effect and the mechanisms where cells can express this metabolic adaptation, researchers subjected nonmalignant cells to the harsh tumor microenvironment that is present during early carcinogenesis, known as ductal carcinoma in situ. In a new research article, the team shows that these conditions select for cells to express a Warburg Effect.

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New discovery in breast cancer treatment

Researchers have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease.

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New discovery in breast cancer treatment

Researchers have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease.

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New discovery in breast cancer treatment

Researchers have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease.

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New computational tool reliably differentiates between cancer and normal cells from single-cell RNA-sequencing data

Researchers have developed a new computational tool to accurately differentiate between cancer cells and normal cells when analyzing large single-cell RNA-sequencing data.

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Cancer models created by mechanical engineers offer new insight into tumor growth

Engineers have developed in vitro -- in the lab -- lymphatic vessel model to study the growth of tumor emboli, collections of tumor cells within vessels that are often associated with increased metastasis and tumor recurrence.

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Early warning sign for heart disease

The build-up of calcium in a major artery outside of the heart could predict future heart attack or stroke, a new study has demonstrated.

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Early warning sign for heart disease

The build-up of calcium in a major artery outside of the heart could predict future heart attack or stroke, a new study has demonstrated.

from Women's Health News -- ScienceDaily https://ift.tt/38FQrRt

The true cost of chemotherapy

New research reveals the non-healthcare costs of chemotherapy for breast cancer patients. It includes the cost of lost productivity, work absence, and 'out-of-pocket' personal costs such as paying for transport and parking for treatment, the cost of wigs and new bras, and over the counter medications. The research team say that better targeting of treatment could help avoid placing unnecessary costs upon patients, their caregivers and wider society.

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Scientists reveal how gut microbes can influence bone strength in mice

Gut microbes passed from female mice to their offspring, or shared between mice that live together, may influence the animals' bone mass.

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Scientists reveal how gut microbes can influence bone strength in mice

Gut microbes passed from female mice to their offspring, or shared between mice that live together, may influence the animals' bone mass.

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New drug form may help treat osteoporosis, calcium-related disorders

Innovators have developed a stabilized form of human calcitonin, which is a peptide drug already used for people with osteoporosis. Researchers created a prodrug form of the peptide hormone to increase its effectiveness as an osteoporosis treatment.

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New drug form may help treat osteoporosis, calcium-related disorders

Innovators have developed a stabilized form of human calcitonin, which is a peptide drug already used for people with osteoporosis. Researchers created a prodrug form of the peptide hormone to increase its effectiveness as an osteoporosis treatment.

from Women's Health News -- ScienceDaily https://ift.tt/2JRMaAK

Long-term study finds dozens of new genetic markers associated with lifetime bone growth

A multidisciplinary team of researchers has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing.

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Heat treatment may make chemotherapy more effective

The study found that 'loading' a chemotherapy drug on to tiny magnetic particles that can heat up the cancer cells at the same time as delivering the drug to them was up to 34% more effective at destroying the cancer cells than the chemotherapy drug without added heat.

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Long-term study finds dozens of new genetic markers associated with lifetime bone growth

A multidisciplinary team of researchers has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing.

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Gut microbe may promote breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research.

from Breast Cancer News -- ScienceDaily https://ift.tt/3rVraKN

Gut microbe may promote breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research.

from Women's Health News -- ScienceDaily https://ift.tt/3rVraKN

Gut microbe may promote breast cancers

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research.

from Women's Health News -- ScienceDaily https://ift.tt/3rVraKN

Link between dietary fiber and depression partially explained by gut-brain interactions

Fiber is a commonly recommended part of a healthy diet. That's because it's good for your health in so many ways -- from weight management to reducing the risk of diabetes, heart disease, and some types of cancer. A new study also finds that it might be linked with a reduced risk of depression, especially in premenopausal women.

from Women's Health News -- ScienceDaily https://ift.tt/3njWQpE

Link between dietary fiber and depression partially explained by gut-brain interactions

Fiber is a commonly recommended part of a healthy diet. That's because it's good for your health in so many ways -- from weight management to reducing the risk of diabetes, heart disease, and some types of cancer. A new study also finds that it might be linked with a reduced risk of depression, especially in premenopausal women.

from Women's Health News -- ScienceDaily https://ift.tt/3njWQpE

Statins may protect the heart from chemotherapy treatment of early breast cancer

Women who take statins, the common cholesterol-lowering medication, during chemotherapy with anthracyclines for early-stage breast cancer are half as likely to require emergency department visits or hospitalization for heart failure in the 5 years after chemotherapy.

from Women's Health News -- ScienceDaily https://ift.tt/2MAyc7j

Statins may protect the heart from chemotherapy treatment of early breast cancer

Women who take statins, the common cholesterol-lowering medication, during chemotherapy with anthracyclines for early-stage breast cancer are half as likely to require emergency department visits or hospitalization for heart failure in the 5 years after chemotherapy.

from Breast Cancer News -- ScienceDaily https://ift.tt/2MAyc7j

Statins may protect the heart from chemotherapy treatment of early breast cancer

Women who take statins, the common cholesterol-lowering medication, during chemotherapy with anthracyclines for early-stage breast cancer are half as likely to require emergency department visits or hospitalization for heart failure in the 5 years after chemotherapy.

from Women's Health News -- ScienceDaily https://ift.tt/2MAyc7j

More women embracing 'going flat' after mastectomy

A growing number of women forgoing reconstruction after a mastectomy say they're satisfied with their choice, even as some did not feel supported by their physician, according to a new study.

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