New analytical model detects mutations in breast cancer

Researchers have developed a computational model which is effective in detecting and identifying genetic mutations in breast tumors. The study, the largest of its kind in the world, includes results from over 3,200 patients with breast cancer.

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Regulatory T cells could lead to new immunotherapies aimed at treating multiple sclerosis

Researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).

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Blood vessel growth in muscle is reduced in women after menopause

A new study demonstrates that formation of small blood vessels is impaired in the muscle tissue of postmenopausal women. The study's findings highlight the importance of physical activity for women prior to and during menopause, as a means to prevent the development of disease later in life.

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'Trojan horse' approach to kill cancer cells without using drugs

Cancer cells are killed in lab experiments and tumor growth reduced in mice, using a new approach that turns a nanoparticle into a 'Trojan horse' that causes cancer cells to self-destruct.

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Higher dementia risk in women with prolonged fertility

Women with a longer reproductive period had an elevated risk for dementia in old age, compared with those who were fertile for a shorter period, a population-based study.

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Combining two precision medicines can treat drug-resistant cancers

Launching a dual-pronged attack on tumours using a combination of two innovative precision medicines could treat patients with multiple common cancers, a new clinical trial shows.

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Botox for TMJ disorders may not lead to bone loss in the short term, but more research is needed

Botox injections to manage jaw and facial pain do not result in clinically significant changes in jaw bone when used short term and in low doses, according to researchers. However, they found evidence of bone loss when higher doses were used.

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Stronger bones thanks to heat and microbiota

Osteoporosis is characterized by a deterioration of the bones and an increased risk of fractures. With one third of postmenopausal women affected, it is a major public health problem. A research team has observed that exposure to warmer ambient temperatures increases bone strength and prevents the loss of bone density. This phenomenon is linked to a change in the composition of gut microbiota and makes hopes for osteoporosis treatments.

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New way to target some rapidly dividing cancer cells, leaving healthy cells unharmed

Scientists say they have found a new way to kill some multiplying human breast cancer cells by selectively attacking the core of their cell division machinery.

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Women's heart health linked to age at first menstrual period

Early menarche has been associated with many cardiovascular disease (CVD) risk factors, but little is known about its association with overall heart health. One new study suggests that age at menarche plays an important role in maintaining and improving cardiovascular health, although there are a number of age differences.

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Brain astrocytes show metabolic alterations in Parkinson's disease

A new study using induced pluripotent stem cell (iPSC) technology links astrocyte dysfunction to Parkinson's disease (PD) pathology. The study highlights the role of brain astrocyte cells in PD pathology and the potential of iPSC-derived cells in disease modelling and drug discovery.

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Endometriosis: No cure, but diagnosis could avert surgery

176 million women worldwide who have endometriosis, a chronic, painful gynaecological condition. It affects nearly three times as many women as breast cancer.

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Personal use of permanent hair dye not associated with greater risk of most cancers or cancer death

Women who use permanent hair dye products to colour their hair at home do not experience greater risk of most cancers or greater cancer related mortality.

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Exposure to workplace sexual harassment linked to an increased risk of suicidal behavior

Workers who have been exposed to sexual harassment in their workplace are at greater risk of suicide and attempting suicide, a new study finds.

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Effective cancer immunotherapy further linked to regulating a cell 'suicide' gene

Researchers have added to evidence that a gene responsible for turning off a cell's natural 'suicide' signals may also be the culprit in making breast cancer and melanoma cells resistant to therapies that use the immune system to fight cancer.

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Cancer cells take over blood vessels to spread

In laboratory studies, researchers observed a key step in how cancer cells may spread from a primary tumor to a distant site within the body, a process known as metastasis.

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Venom from honeybees found to kill aggressive breast cancer cells

Honeybee venom induces cancer cell death in hard to treat triple-negative breast cancer with minimal effect on healthy cells, new research finds.

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