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Monday, July 27, 2020

A new way to target cancers using 'synthetic lethality'

Researchers report that inhibiting a key enzyme caused human cancer cells associated with two major types of breast and ovarian cancer to die and in mouse studies reduced tumor growth.

from Women's Health News -- ScienceDaily https://ift.tt/2DdziRG

A new way to target cancers using 'synthetic lethality'

Researchers report that inhibiting a key enzyme caused human cancer cells associated with two major types of breast and ovarian cancer to die and in mouse studies reduced tumor growth.

from Women's Health News -- ScienceDaily https://ift.tt/2DdziRG

Sunday, July 26, 2020

Antiviral method against herpes paves the way for combating incurable viral infections

Researchers have discovered a new method to treat human herpes viruses. The new broad-spectrum method targets physical properties in the genome of the virus rather than viral proteins, which have previously been targeted. The treatment consists of new molecules that penetrate the protein shell of the virus and prevent genes from leaving the virus to infect the cell. It does not lead to resistance and acts independently of mutations in the genome of the virus.

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Saturday, July 25, 2020

Study finds global trends in women's breast cancer show cause for concern

Breast cancer rates among women globally are on the rise, but new research is uncovering trends related to age and where you live that could help target prevention measures to improve the situation.

from Women's Health News -- ScienceDaily https://ift.tt/2CNycMO

Study finds global trends in women's breast cancer show cause for concern

Breast cancer rates among women globally are on the rise, but new research is uncovering trends related to age and where you live that could help target prevention measures to improve the situation.

from Breast Cancer News -- ScienceDaily https://ift.tt/2CNycMO

Friday, July 24, 2020

Immune system -- Knocked off balance

Instead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune diseases and allergies. A team has now dissected how mast cells regulate their calcium levels to keep the immune response under control.

from Women's Health News -- ScienceDaily https://ift.tt/2WT26Gh

Triple negative breast cancer meets its match

One member of a larger family of oxygen sensing enzymes could offer a viable target for triple negative breast cancer (TNBC), researchers report in a new study. The findings might offer hope to this subset of patients who have few effective treatment options and often face a poor prognosis.

from Breast Cancer News -- ScienceDaily https://ift.tt/3jzZAhL

Thursday, July 23, 2020

Calcium channel subunits play a major role in autism spectrum disorders

Neurobiologists have found new evidence that specific calcium channel subunits play a crucial role in the development of excitatory and inhibitory synapses.

from Women's Health News -- ScienceDaily https://ift.tt/3jDWSrQ

Wednesday, July 22, 2020

Cancer metabolic pathway identified as target for therapy

Fighting cancer often means employing a suite of techniques to target the tumor and prevent it from growing and spreading to other parts of the body. It's no small feat -- the American Cancer Society predicts roughly 1.8 million new cases of cancer in the country in 2020, underscoring the need to identify additional ways to outsmart the runaway cells.

from Women's Health News -- ScienceDaily https://ift.tt/3jvsfEO

Cancer metabolic pathway identified as target for therapy

Fighting cancer often means employing a suite of techniques to target the tumor and prevent it from growing and spreading to other parts of the body. It's no small feat -- the American Cancer Society predicts roughly 1.8 million new cases of cancer in the country in 2020, underscoring the need to identify additional ways to outsmart the runaway cells.

from Women's Health News -- ScienceDaily https://ift.tt/3jvsfEO

Fasting diet could boost breast cancer therapy

A team of scientists has found that a fasting-mimicking diet combined with hormone therapy has the potential to help treat breast cancer, according to newly published animal studies and small clinical trials in humans.

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Early menstruation linked to increased menopause symptoms

Early menstruation increases the likelihood of hot flushes and nights sweats decades later at menopause, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/3eTCYVS

Monday, July 20, 2020

New nano drug candidate kills aggressive breast cancer cells

Researchers have developed a new drug candidate that kills triple negative breast cancer cells. The discovery will help clinicians target breast cancer cells directly, while avoiding the adverse, toxic side effects of chemotherapy.

from Women's Health News -- ScienceDaily https://ift.tt/2WGhwh3

New nano drug candidate kills aggressive breast cancer cells

Researchers have developed a new drug candidate that kills triple negative breast cancer cells. The discovery will help clinicians target breast cancer cells directly, while avoiding the adverse, toxic side effects of chemotherapy.

from Breast Cancer News -- ScienceDaily https://ift.tt/2WGhwh3

New nano drug candidate kills aggressive breast cancer cells

Researchers have developed a new drug candidate that kills triple negative breast cancer cells. The discovery will help clinicians target breast cancer cells directly, while avoiding the adverse, toxic side effects of chemotherapy.

from Women's Health News -- ScienceDaily https://ift.tt/2WGhwh3

Saturday, July 18, 2020

Widening cancer gene testing is cost effective and could prevent millions of cancer cases

Screening entire populations for breast and ovarian cancer gene mutations could prevent millions more breast and ovarian cancer cases across the world compared to current clinical practice, according to an international study. The research also shows that it is cost effective in high and upper-middle income countries.

from Women's Health News -- ScienceDaily https://ift.tt/397mrws

Widening cancer gene testing is cost effective and could prevent millions of cancer cases

Screening entire populations for breast and ovarian cancer gene mutations could prevent millions more breast and ovarian cancer cases across the world compared to current clinical practice, according to an international study. The research also shows that it is cost effective in high and upper-middle income countries.

from Women's Health News -- ScienceDaily https://ift.tt/397mrws

Widening cancer gene testing is cost effective and could prevent millions of cancer cases

Screening entire populations for breast and ovarian cancer gene mutations could prevent millions more breast and ovarian cancer cases across the world compared to current clinical practice, according to an international study. The research also shows that it is cost effective in high and upper-middle income countries.

from Breast Cancer News -- ScienceDaily https://ift.tt/397mrws

Friday, July 17, 2020

Potential treatment for rare degenerative disease

A pharmacology professor and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment.

from Women's Health News -- ScienceDaily https://ift.tt/2DUdn2u

Potential treatment for rare degenerative disease

A pharmacology professor and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment.

from Women's Health News -- ScienceDaily https://ift.tt/2DUdn2u

Wednesday, July 15, 2020

Credit-card sized tool provides new insights into how cancer cells invade host tissues

Researchers have developed a credit-card sized tool for growing cancer cells outside the human body, which they believe will enhance their understanding of breast cancer metastasis. The device reproduces various environments within the human body where breast cancer cells live. Studying the cells as they go through the process of invasion and metastasis could point the way toward new biomarkers and drugs to diagnose and treat cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/3j6g5C0

Friday, July 10, 2020

Response to stimulation in IVF may predict longer term health risks

A follow-up study of almost 20,000 young women who had a first cycle of IVF in Denmark between 1995 and 2014 indicates that those who responded poorly to treatment, with few eggs collected, are at a significantly increased risk of later age-related diseases.

from Women's Health News -- ScienceDaily https://ift.tt/3ehljHp

Response to stimulation in IVF may predict longer term health risks

A follow-up study of almost 20,000 young women who had a first cycle of IVF in Denmark between 1995 and 2014 indicates that those who responded poorly to treatment, with few eggs collected, are at a significantly increased risk of later age-related diseases.

from Women's Health News -- ScienceDaily https://ift.tt/3ehljHp

Thursday, July 9, 2020

New link between calcium and cardiolipin in heart defects

To function properly, the heart needs energy from cells' powerhouses, the mitochondria. In turn, mitochondria boost their energy output when calcium levels rise around them, a signal that more energy is needed. A new study shows that a shortage of cardiolipin, a type of fat, in the mitochondrial membrane, prevents calcium from entering mitochondria. The result helps explain heart and muscle weakness in the rare genetic disorder Barth syndrome.

from Women's Health News -- ScienceDaily https://ift.tt/2ChHtMu

New link between calcium and cardiolipin in heart defects

To function properly, the heart needs energy from cells' powerhouses, the mitochondria. In turn, mitochondria boost their energy output when calcium levels rise around them, a signal that more energy is needed. A new study shows that a shortage of cardiolipin, a type of fat, in the mitochondrial membrane, prevents calcium from entering mitochondria. The result helps explain heart and muscle weakness in the rare genetic disorder Barth syndrome.

from Women's Health News -- ScienceDaily https://ift.tt/2ChHtMu

Monday, July 6, 2020

One in five Georgian Londoners had syphilis by their mid-30s

250 years ago, over one-fifth of Londoners had contracted syphilis by their 35th birthday, historians have calculated.

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Coronary calcium scoring: Personalized preventive care for those most at risk

An imaging test called coronary calcium scoring can help doctors to make the right recommendation about the use of statin therapy. The test is a 10-minute CT (computed tomography) scan looking for calcium deposits in the arteries supplying blood to the heart. Calcium deposits indicate the presence of coronary plaque, also known as atherosclerosis.

from Women's Health News -- ScienceDaily https://ift.tt/3f5FZDF

Coronary calcium scoring: Personalized preventive care for those most at risk

An imaging test called coronary calcium scoring can help doctors to make the right recommendation about the use of statin therapy. The test is a 10-minute CT (computed tomography) scan looking for calcium deposits in the arteries supplying blood to the heart. Calcium deposits indicate the presence of coronary plaque, also known as atherosclerosis.

from Women's Health News -- ScienceDaily https://ift.tt/3f5FZDF

Sunday, July 5, 2020

'Biologically relevant' levels of a fertility hormone are detected in human hair samples

The prospect of a non-invasive test of ovarian reserve is a little closer following results from a study showing that measurement of a fertility hormone can be accurately taken from a sample of human hair.

from Women's Health News -- ScienceDaily https://ift.tt/31NKK0A

'Biologically relevant' levels of a fertility hormone are detected in human hair samples

The prospect of a non-invasive test of ovarian reserve is a little closer following results from a study showing that measurement of a fertility hormone can be accurately taken from a sample of human hair.

from Women's Health News -- ScienceDaily https://ift.tt/31NKK0A

Thursday, July 2, 2020

Hot flushes and night sweats linked to 70% increase in cardiovascular disease

New research has found that women who have hot flushes and night sweats after menopause are 70 per cent more likely to have heart attacks, angina and strokes.

from Women's Health News -- ScienceDaily https://ift.tt/2YSe3x8

Hot flushes and night sweats linked to 70% increase in cardiovascular disease

New research has found that women who have hot flushes and night sweats after menopause are 70 per cent more likely to have heart attacks, angina and strokes.

from Women's Health News -- ScienceDaily https://ift.tt/2YSe3x8