Whole genome sequencing could enable personalized cancer treatment

Whole genome sequencing of tumour cells could help predict the prognosis of a patient's cancer and offer clues to identify the most effective treatment, suggests an international study.

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Inflammation amps up neurite growth, gene expression involved in heat, cold sensitivity

Inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal -- but not physical- sensations in mice.

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Menopausal night sweats linked with cognitive dysfunction

Experts frequently tout the value of a good night's sleep. However, a new study casts doubt on the value of sleep time suggesting that women who experience night sweats are more vulnerable to cognitive dysfunction as their sleep duration increases.

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Onion and garlic consumption may reduce breast cancer risk

In the first population-based study to examine the association between onion and garlic consumption and breast cancer in Puerto Rico, researchers found that women who ate sofrito more than once per day had a 67% decreased breast cancer risk.

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Mummy study: Heart disease was bigger issue for human ancestors than initially thought

A new imaging study of the mummified arteries of people who lived thousands of years ago revealed that their arteries were more clogged than originally thought, according to a proof-of-concept study.

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Mummy study: Heart disease was bigger issue for human ancestors than initially thought

A new imaging study of the mummified arteries of people who lived thousands of years ago revealed that their arteries were more clogged than originally thought, according to a proof-of-concept study.

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New vaccine prevents herpes in mice, guinea pigs

A novel vaccine protected almost all mice and guinea pigs exposed to a new herpes virus. This may lead to the vaccine being tested in human studies.

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New target regulating mitochondria during stress

Like an emergency response team that is called into action to save lives, stress response proteins in the heart are activated during a heart attack to help prevent cell death. As part of this process, researchers show for the first time that one of these specialized emergency responder proteins, known as MCUB, temporarily decreases harmful levels of calcium transport into mitochondria, the energy-generating batteries of cells.

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New target regulating mitochondria during stress

Like an emergency response team that is called into action to save lives, stress response proteins in the heart are activated during a heart attack to help prevent cell death. As part of this process, researchers show for the first time that one of these specialized emergency responder proteins, known as MCUB, temporarily decreases harmful levels of calcium transport into mitochondria, the energy-generating batteries of cells.

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Brain tumors form synapses with healthy neurons

Scientists have shown for the first time that severe brain cancers integrate into the brain's wiring.

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The path of breast-to-brain cancer metastasis

Scientists have discovered a signaling pathway that breast tumors exploit to metastasize to the brain.

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Brain tumors form synapses with healthy neurons

Scientists have shown for the first time that severe brain cancers integrate into the brain's wiring.

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The path of breast-to-brain cancer metastasis

Scientists have discovered a signaling pathway that breast tumors exploit to metastasize to the brain.

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The path of breast-to-brain cancer metastasis

Scientists have discovered a signaling pathway that breast tumors exploit to metastasize to the brain.

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Cancer cells turn to cannibalism to survive chemotherapy, study suggests

Researchers have discovered that some cancer cells survive chemotherapy by eating their neighboring tumor cells. The study suggests that this act of cannibalism provides these cancer cells with the energy they need to stay alive and initiate tumor relapse after the course of treatment is completed.

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Screening mammography could benefit men at high risk of breast cancer

Selective mammography screening can provide potentially lifesaving early detection of breast cancer in men who are at high risk for the disease, according to a new landmark study.

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Novel approach to ultrasound raises possibility of new medical applications

A new ultrasound technique provides a non-invasive way of assessing bone structure on the microscale. Researchers hope to fine-tune the technique for use in assessing osteoporosis risk and treatment.

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Screening mammography could benefit men at high risk of breast cancer

Selective mammography screening can provide potentially lifesaving early detection of breast cancer in men who are at high risk for the disease, according to a new landmark study.

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Novel approach to ultrasound raises possibility of new medical applications

A new ultrasound technique provides a non-invasive way of assessing bone structure on the microscale. Researchers hope to fine-tune the technique for use in assessing osteoporosis risk and treatment.

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Screening mammography could benefit men at high risk of breast cancer

Selective mammography screening can provide potentially lifesaving early detection of breast cancer in men who are at high risk for the disease, according to a new landmark study.

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Later puberty and later menopause associated with lower risk of type 2 diabetes in women

New research shows that use of the contraceptive pill and longer menstrual cycles are associated with a higher risk of developing type 2 diabetes (T2D), while later puberty and later menopause are associated with lower risk.

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Later puberty and later menopause associated with lower risk of type 2 diabetes in women

New research shows that use of the contraceptive pill and longer menstrual cycles are associated with a higher risk of developing type 2 diabetes (T2D), while later puberty and later menopause are associated with lower risk.

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Starting HIV treatment in ERs may be key to ending HIV spread worldwide

Researchers say they have evidence that hospital emergency departments (EDs) worldwide may be key strategic settings for curbing the spread of HIV infections in hard-to-reach populations if the EDs jump-start treatment and case management as well as diagnosis of the disease.

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High social support associated with less violence among male teens in urban neighborhoods

Researchers find that the presence of adult social support is linked to less violence among at-risk teen boys.

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Tiny bubbles in our body could fight cancer better than chemo

Healthy cells in our body release nano-sized bubbles that transfer genetic material such as DNA and RNA to other cells. It's your DNA that stores the important information necessary for RNA to produce proteins and make sure they act accordingly. These bubbly extracellular vesicles could become mini treatment transporters, carrying a combination of therapeutic drugs and genes that target cancer cells and kill them, according to new research from Michigan State University and Stanford University.

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Cells that make bone marrow also travel to the womb to help pregnancy

Bone marrow-derived cells play a role in changes to the mouse uterus before and during pregnancy, enabling implantation of the embryo and reducing pregnancy loss, according to new research.

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Cells that make bone marrow also travel to the womb to help pregnancy

Bone marrow-derived cells play a role in changes to the mouse uterus before and during pregnancy, enabling implantation of the embryo and reducing pregnancy loss, according to new research.

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Calcium channel blockers may be effective in treating memory loss in Alzheimer's disease

Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have identified that calcium channel blockers may be effective in treating memory loss.

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Calcium channel blockers may be effective in treating memory loss in Alzheimer's disease

Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have identified that calcium channel blockers may be effective in treating memory loss.

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Breast cancer cells 'stick together' to spread through the body during metastasis

Researchers have discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis. Their conclusions, obtained through laboratory experiments and in mouse models, help explain how metastasis works in the most common form of breast cancer, invasive ductal carcinoma. E-cadherin appears to limit molecular stresses within the cancer cells and allow them to survive long enough to form new tumors.

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How babies absorb calcium could be key to treating osteoporosis in seniors

New research reveals the mechanism that allows breastfeeding babies to absorb large amounts of calcium and build healthy bones -- a discovery that could lead to treatment for osteoporosis and other bone diseases later in life. The researchers identified calcium-absorbing channels in the lower two-thirds of the small intestines of breastfed infant mice.

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Breast cancer cells 'stick together' to spread through the body during metastasis

Researchers have discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis. Their conclusions, obtained through laboratory experiments and in mouse models, help explain how metastasis works in the most common form of breast cancer, invasive ductal carcinoma. E-cadherin appears to limit molecular stresses within the cancer cells and allow them to survive long enough to form new tumors.

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How babies absorb calcium could be key to treating osteoporosis in seniors

New research reveals the mechanism that allows breastfeeding babies to absorb large amounts of calcium and build healthy bones -- a discovery that could lead to treatment for osteoporosis and other bone diseases later in life. The researchers identified calcium-absorbing channels in the lower two-thirds of the small intestines of breastfed infant mice.

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Breast cancer cells 'stick together' to spread through the body during metastasis

Researchers have discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis. Their conclusions, obtained through laboratory experiments and in mouse models, help explain how metastasis works in the most common form of breast cancer, invasive ductal carcinoma. E-cadherin appears to limit molecular stresses within the cancer cells and allow them to survive long enough to form new tumors.

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Medical marijuana laws impact use among sexual minorities differently than heterosexuals

Bisexual women had higher rates of past-year and daily marijuana use compared to heterosexual women, and gay/lesbian women were also more likely to report daily marijuana use and past year medical marijuana use than heterosexual women. While previous research has explored the association between state-level medical marijuana laws and marijuana use and MU disorder among the general US population, this is among the first to explore this relationship for lesbian, gay and bisexual individuals.

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FAK protein linked to chemotherapy resistance in ovarian cancer

A new study links changes in the gene for the protein focal adhesion kinase, or FAK, to ovarian cancer's ability to survive chemotherapy.

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Vitamin D: How much is too much of a good thing?

A three-year study has shown that there is no benefit in taking high doses of vitamin D. More research is required to determine if high doses may actually compromise bone health.

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FAK protein linked to chemotherapy resistance in ovarian cancer

A new study links changes in the gene for the protein focal adhesion kinase, or FAK, to ovarian cancer's ability to survive chemotherapy.

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Vitamin D: How much is too much of a good thing?

A three-year study has shown that there is no benefit in taking high doses of vitamin D. More research is required to determine if high doses may actually compromise bone health.

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Breast cancer gene a potential target for childhood liver cancer treatment

Hepatoblastoma is a rare liver cancer that mainly affects infants and young children. Researchers confirmed that breast cancer gene GREB1 plays a major role in hepatoblastoma cell proliferation. By interfering with GREB1 protein production, tumor formation was inhibited in a mouse liver cancer model, suggesting this approach could be used to develop a targeted hepatoblastoma therapy.

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Breast cancer can form 'sleeper cells' after drug treatment

Breast cancer medicines may force some cancer cells into 'sleeper mode,' allowing them to potentially come back to life years after initial treatment.

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Breast cancer can form 'sleeper cells' after drug treatment

Breast cancer medicines may force some cancer cells into 'sleeper mode,' allowing them to potentially come back to life years after initial treatment.

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Breast cancer can form 'sleeper cells' after drug treatment

Breast cancer medicines may force some cancer cells into 'sleeper mode,' allowing them to potentially come back to life years after initial treatment.

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