How a Y chromosome gene may shape the course of heart valve disease

Researchers have shed new light on how a type of heart valve disease -- aortic valve stenosis -- progresses differently in males and females.

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AI-powered mammograms: A new window into heart health

Mammograms, with the help of artificial intelligence (AI) models, may reveal much more than cancer, according to a new study. The findings highlight how these important cancer screening tools can also be used to assess the amount of calcium buildup in the arteries within breast tissue -- an indicator of cardiovascular health.

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Vaccine may improve breast cancer treatment outcomes

Researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer. The innovative approach targets human epidermal growth factor receptor 2-positive, estrogen receptor-negative (HER2-positive, ER-negative) breast cancer and has shown encouraging results in a recent pilot study. The study combined the HER2-targeting dendritic cell vaccines with standard chemotherapy, demonstrating both safety and positive response rates.

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Vaccine may improve breast cancer treatment outcomes

Researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer. The innovative approach targets human epidermal growth factor receptor 2-positive, estrogen receptor-negative (HER2-positive, ER-negative) breast cancer and has shown encouraging results in a recent pilot study. The study combined the HER2-targeting dendritic cell vaccines with standard chemotherapy, demonstrating both safety and positive response rates.

from Women's Health News -- ScienceDaily https://ift.tt/E1SqgKG

Slow, silent 'scream' of epithelial cells detected for first time

It has long been thought that only nerve and heart cells use electric impulses to communicate, while epithelial cells -- which compose the linings of our skin, organs and body cavities -- are mute, serving mostly as protective barriers that can absorb and secrete various substances. But researchers have now upended the status quo by showing that epithelial cells do indeed 'talk' to each other, albeit with slow electrical signals.

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Oxytocin system of breastfeeding affected in mothers with postnatal depression

The oxytocin system -- which helps release breast milk and strengthens the bond between mother and baby -- may be affected during breastfeeding in mothers experiencing postnatal depression.

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New antibody reduces tumor growth in treatment-resistant breast and ovarian cancers

A new type of antibody which stimulates the immune system to target cancer cells slows tumour growth, according to new research.

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Nwd1 gene deletion triggers MASH-like pathology in mice

Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their specific roles in the progression of disease remain unknown. To address this gap, researchers conducted a series of experiments that identified the NACHT and WD repeat domain-containing protein 1 (Nwd1) gene and its role in liver pathogenesis. This breakthrough represents an important step toward establishing new therapeutic targets for MASH.

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Exercise and healthy eating behavior together provide the best protection against cardiovascular diseases

Researchers have found that women who exhibit disturbed eating behaviors and engage in low physical activity tend to have more central body fat and a higher risk of metabolic low-grade inflammation. This condition increases the risk of cardiovascular diseases, which become more prevalent after menopause. However, the combined effect of exercise and healthy eating behavior offers the most effective protection against inflammation and may also reduce it after menopause.

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Diabetes drug could help cancer patients make better recovery

Research shows that a common type of diabetes medication could help cancer patients make a better long-term recovery. Many cancer patients go on to develop heart failure -- because of the cancer itself and also due to chemotherapy. But a study shows that a type of diabetes drug, called an SGLT2 inhibitor, may help protect the heart during and after cancer treatment. The medication has been shown to be beneficial in reducing heart failure or heart failure hospitalisation in cancer patients and survivors.

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