Tumor-induced B cell changes reveal potential biomarker for treatment response in triple negative breast cancer

Researchers have discovered new insights into tumor-induced B cell changes in blood and bone marrow of triple negative breast cancer patients. The findings show two distinct patterns of B cell abnormalities that could serve as blood biomarkers for determining likelihood of response to standard-of-care chemotherapy and immunotherapy.

from Breast Cancer News -- ScienceDaily https://ift.tt/PE08aXh

Antibody-drug conjugate found effective against brain metastases in patients with HER2-positive breast cancer

A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer. The findings, from an international clinical trial, reinforce earlier findings of the benefits of the drug -- trastuzumab deruxtecan (T-DXd), an antibody-drug conjugate -- in these patients, trial leaders say.

from Breast Cancer News -- ScienceDaily https://ift.tt/rOTBWhl

New proteins involved in regulating the cell membrane

Scientists have uncovered new details about how cells manage the distribution of lipids in their cell membrane. These lipids, known as phospholipids, are arranged in a bilayer of membranes, regulating entry and exit of certain molecules to maintain a stable internal environment.

from Women's Health News -- ScienceDaily https://ift.tt/yLWNKJC

Genes with strong impact on menopause timing also link to cancer risk

The team first looked at variation in data from genetic sequencing of 106,973 post-menopausal female participants in the UK Biobank study. Researchers focused on rare types of genetic changes which cause a loss of the protein, and investigated their effect on the timing of menopause. The genetic changes studied are all rare in the population, however their influence on menopause is five times greater than the impact of any previously identified common genetic variant.

from Women's Health News -- ScienceDaily https://ift.tt/1eGmNIi

Novel bone cancer therapy has 99% success rate, tests show

Bioactive glasses, a filling material which can bond to tissue and improve the strength of bones and teeth, has been combined with gallium to create a potential treatment for bone cancer. Tests in labs have found that bioactive glasses doped with the metal have a 99 percent success rate of eliminating cancerous cells and can even regenerate diseased bones.

from Women's Health News -- ScienceDaily https://ift.tt/Ff7Ho8B

Low-impact yoga and exercise found to help older women manage urinary incontinence

New research finds that 12 weeks of low-impact exercise classes reduced daily episodes of urinary incontinence by more than half.

from Women's Health News -- ScienceDaily https://ift.tt/y31akWx

Skin fungus colonization accelerates breast cancer tumor growth

A new study shows that skin fungus colonization of Malassezia globosa speeds up breast cancer tumor growth.

from Women's Health News -- ScienceDaily https://ift.tt/ateLIkw

Skin fungus colonization accelerates breast cancer tumor growth

A new study shows that skin fungus colonization of Malassezia globosa speeds up breast cancer tumor growth.

from Breast Cancer News -- ScienceDaily https://ift.tt/ateLIkw

False-positive mammograms discourage some women from future screenings

A false-positive mammogram may deter women from future screenings, according to a new study. But staying on schedule remains key to early detection of cancer.

from Women's Health News -- ScienceDaily https://ift.tt/64kvy0r

False-positive mammograms discourage some women from future screenings

A false-positive mammogram may deter women from future screenings, according to a new study. But staying on schedule remains key to early detection of cancer.

from Breast Cancer News -- ScienceDaily https://ift.tt/64kvy0r