How gonorrhea develops resistance to antibiotics

As public health officials worry about the emergence of antibiotic-resistant gonorrhea, researchers are tracing how antibiotics bind to a gonococcal protein, information that can help lead to new antimicrobials.

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Scorpion toxin that targets 'wasabi receptor' may help solve mystery of chronic pain

Researchers have discovered a scorpion toxin that targets the 'wasabi receptor,' a chemical-sensing protein found in nerve cells that's responsible for the sinus-jolting sting of wasabi. Because the toxin triggers a pain response, scientists think it can be used as a tool for studying chronic pain and inflammation, and may eventually lead to the development of new kinds of non-opioid pain relievers.

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Scorpion toxin that targets 'wasabi receptor' may help solve mystery of chronic pain

Researchers have discovered a scorpion toxin that targets the 'wasabi receptor,' a chemical-sensing protein found in nerve cells that's responsible for the sinus-jolting sting of wasabi. Because the toxin triggers a pain response, scientists think it can be used as a tool for studying chronic pain and inflammation, and may eventually lead to the development of new kinds of non-opioid pain relievers.

from Women's Health News -- ScienceDaily https://ift.tt/2TT0Znl

New pharmaceutical target reverses osteoporosis in mice

Biomedical engineers have discovered that an adenosine receptor called A2B can be pharmaceutically activated to reverse bone degradation caused by osteoporosis in mouse models of the disease.

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New pharmaceutical target reverses osteoporosis in mice

Biomedical engineers have discovered that an adenosine receptor called A2B can be pharmaceutically activated to reverse bone degradation caused by osteoporosis in mouse models of the disease.

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Parasite needs chemical (lipid/nutrient) in cat intestines for sex

Toxoplasma gondii is a microbial parasite that infects humans and but needs cats to complete its full life cycle. New research shows why: the sexual phase of the parasite's life cycle requires linoleic acid, a nutrient/lipid found at uniquely high levels in the felines, because cats lack a key enzyme for breaking it down.

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Repeated semen exposure promotes host resistance to infection in preclinical HIV model

Contrary to the long-held view that semen can only act as a way to transmit HIV-1 from men to women, scientists found that frequent and sustained semen exposure can change the characteristics of the circulating and vaginal tissue immune cells that are targets for infection, reducing the susceptibility to a future infection.

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Family history of diabetes linked to increased bone mineral density

The association between type 2 diabetes and increased fracture risk is well documented. However, little was known about the possible effect of family history of diabetes on bone mineral density (BMD). A study now confirms that a history of first-degree family members with diabetes is linked to increased BMD as well as to insulin resistance.

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Family history of diabetes linked to increased bone mineral density

The association between type 2 diabetes and increased fracture risk is well documented. However, little was known about the possible effect of family history of diabetes on bone mineral density (BMD). A study now confirms that a history of first-degree family members with diabetes is linked to increased BMD as well as to insulin resistance.

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What's at the 'heart' of a heartbeat?

A new finding has changed the understanding of the molecular mechanisms leading to atrial fibrillation.

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