The aspirin conundrum: Navigating negative results, age, aging dynamics and equity

A new study examining the role of aspirin in breast cancer treatment reveals critical issues related to health equity and aging that have broad implications for cancer and other disease intervention trials, say researchers.

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Gene-based therapy restores cellular development and function in brain cells from people with Timothy syndrome

In a proof-of-concept study, researchers demonstrated the effectiveness of a potential new therapy for Timothy syndrome, an often life-threatening and rare genetic disorder that affects a wide range of bodily systems, leading to severe cardiac, neurological, and psychiatric symptoms as well as physical differences such as webbed fingers and toes.

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Breast cancer rates rising among Canadian women in their 20s, 30s and 40s

Rates of breast cancer in women under the age of 50 are rising in Canada according to a study which showed an increase in breast cancer diagnoses among females in their twenties, thirties, and forties.

from Breast Cancer News -- ScienceDaily https://ift.tt/TtSWjRq

Breast cancer rates rising among Canadian women in their 20s, 30s and 40s

Rates of breast cancer in women under the age of 50 are rising in Canada according to a study which showed an increase in breast cancer diagnoses among females in their twenties, thirties, and forties.

from Women's Health News -- ScienceDaily https://ift.tt/TtSWjRq

Glial hyper-drive for triggering epileptic seizures

When epileptic patients suffer seizures, their brain is undergoing repetitive and excessive neuronal firing. But what triggers this has stumped scientists for years. Now, researchers have used fluorescence calcium sensors to track astrocytes' role in epileptic seizures, finding that that astrocyte activity starts approximately 20 seconds before the onset of epileptic neuronal hyperactivity.

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Next-generation treatments hitch a ride into cancer cells

Researchers found that a new activator called L687 induces cancer cells to accept delivery of antisense oligonucleotide (ASO) drugs. These drugs can treat cancer by blocking the transfer of messages from genes that encourage cancer growth. Previous methods to deliver ASOs into cells had only limited success. This research will help accelerate the development and delivery of novel ASO cancer therapies.

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AI-assisted breast-cancer screening may reduce unnecessary testing

Researchers showed that AI assistance potentially could improve breast-cancer screening by reducing the number of false positives without missing true positives.

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Nasal spray safely treats recurrent abnormal heart rhythms, clinical trial suggests

A clinical trial showed that a nasal spray that patients administer at home, without a physician, successfully and safely treated recurrent episodes of a condition that causes rapid abnormal heart rhythms. The study provides real-world evidence that a wide range of patients can safely and effectively use the experimental drug, called etripamil, to treat recurrent paroxysmal supraventricular tachycardia (PSVT) episodes at home, potentially sparing them the need for repeated hospital trips for more invasive treatments.

from Women's Health News -- ScienceDaily https://ift.tt/kuQK8Oo

Less extensive breast cancer surgery results in fewer swollen arms

It is possible to leave most of the lymph nodes in the armpit, even if one or two of them have metastases larger than two millimeters. This is shown in a trial enrolling women from five countries. The results open up for gentler surgery for patients with breast cancer.

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