'Exhausted' immune cells in healthy women could be target for breast cancer prevention

People carrying BRCA1 and BRCA2 gene mutations are at high risk of developing breast and ovarian cancer. Researchers have found that changes occur in the immune cells of breast tissue in carriers of BRCA1 and BRCA2 mutations long before breast cancer develops. This raises the possibility of early intervention to prevent the disease, as an alternative to risk-reduction surgery. Drugs already approved for late-stage breast cancer treatment could reactivate the faulty immune cells and keep the breast cells healthy. If successful in mouse models, this preventative therapeutic approach could pave the way for clinical trials in human carriers of BRCA1 and BRCA2 mutations.

from Women's Health News -- ScienceDaily https://ift.tt/5b1Ja0C

'Exhausted' immune cells in healthy women could be target for breast cancer prevention

People carrying BRCA1 and BRCA2 gene mutations are at high risk of developing breast and ovarian cancer. Researchers have found that changes occur in the immune cells of breast tissue in carriers of BRCA1 and BRCA2 mutations long before breast cancer develops. This raises the possibility of early intervention to prevent the disease, as an alternative to risk-reduction surgery. Drugs already approved for late-stage breast cancer treatment could reactivate the faulty immune cells and keep the breast cells healthy. If successful in mouse models, this preventative therapeutic approach could pave the way for clinical trials in human carriers of BRCA1 and BRCA2 mutations.

from Breast Cancer News -- ScienceDaily https://ift.tt/5b1Ja0C

Researchers develop deep learning model to predict breast cancer

Researchers have developed a new, interpretable artificial intelligence (AI) model to predict 5-year breast cancer risk from mammograms, according to a new study.

from Women's Health News -- ScienceDaily https://ift.tt/tgi5Z6J

Researchers develop deep learning model to predict breast cancer

Researchers have developed a new, interpretable artificial intelligence (AI) model to predict 5-year breast cancer risk from mammograms, according to a new study.

from Breast Cancer News -- ScienceDaily https://ift.tt/tgi5Z6J

In the fight against breast cancer, researchers identify malignancy hibernation as the next battleground

There is a surprising dearth of research about how breast cancer cells can go dormant, spread and then resurface years or even decades later, according to a new review of in vitro breast cancer studies.

from Breast Cancer News -- ScienceDaily https://ift.tt/7Ycueqt

In the fight against breast cancer, researchers identify malignancy hibernation as the next battleground

There is a surprising dearth of research about how breast cancer cells can go dormant, spread and then resurface years or even decades later, according to a new review of in vitro breast cancer studies.

from Women's Health News -- ScienceDaily https://ift.tt/7Ycueqt

Fish fed to farmed salmon should be part of our diet, too, study suggests

Scientists found that farmed salmon production leads to an overall loss of essential dietary nutrients. They say that eating more wild 'feed' species directly could benefit our health while reducing aquaculture demand for finite marine resources.

from Women's Health News -- ScienceDaily https://ift.tt/035bR1G

GPS nanoparticle platform precisely delivers therapeutic payload to cancer cells

A newly developed 'GPS nanoparticle' injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers. They tested their approach in human cell lines and in mice to effectively knock down a cancer-causing gene, reporting that the technique may potentially offer a more precise and effective treatment for notoriously hard-to-treat basal-like breast cancers.

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A smart molecule beats the mutation behind most pancreatic cancer

Researchers have designed a candidate drug that could help make pancreatic cancer, which is almost always fatal, a treatable, perhaps even curable, condition.

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Study sheds light on how neurotransmitter receptors transport calcium

A new study is shedding light on our understanding of the molecular origins of some forms of autism and intellectual disability. Researchers were able to successfully capture atomic resolution images of the fast-moving ionotropic glutamate receptor (iGluR) as it transports calcium. iGluRs and their ability to transport calcium are vitally important for many brain functions such as vision or other information coming from sensory organs. Calcium also brings about changes in the signalling capacity of iGluRs and nerve connections which are a key cellular events that lead to our ability to learn new skills and form memories.

from Women's Health News -- ScienceDaily https://ift.tt/xo2r0aN