Unraveling the long history of breast cancer formation

The mechanism by which breast cancer is formed in the cells of mammalian epithelium has been discovered. Although roughly 20 mutations accumulate annually in each epithelial cell until menopause, the mutation rate significantly decreases after menopause. Accumulation also decreased after childbirth, suggesting the effect of estrogen in mammary epithelium.

from Women's Health News -- ScienceDaily https://ift.tt/iWsQY5p

Unraveling the long history of breast cancer formation

The mechanism by which breast cancer is formed in the cells of mammalian epithelium has been discovered. Although roughly 20 mutations accumulate annually in each epithelial cell until menopause, the mutation rate significantly decreases after menopause. Accumulation also decreased after childbirth, suggesting the effect of estrogen in mammary epithelium.

from Breast Cancer News -- ScienceDaily https://ift.tt/iWsQY5p

Estrogen-negative cancers respond to anti-estrogenic therapies

Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models.

from Breast Cancer News -- ScienceDaily https://ift.tt/EHN8jMn

Estrogen-negative cancers respond to anti-estrogenic therapies

Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models.

from Women's Health News -- ScienceDaily https://ift.tt/EHN8jMn

Breast size affects women's attitudes to exercise

Women with larger breasts tend to exercise less frequently and avoid high-intensity exercise and a new study has found much improved participation in recreational group exercises after breast reduction surgery. The new study further strengthens calls for more accessible, publicly funded breast reduction and other interventions in some cases.

from Breast Cancer News -- ScienceDaily https://ift.tt/lzf2L6P

Radiation may not be necessary for patients with low-risk breast cancer

Researchers have found some women with early-stage, low-risk breast cancer may not need radiotherapy after breast conserving surgery.

from Women's Health News -- ScienceDaily https://ift.tt/MbeHZmX

Radiation may not be necessary for patients with low-risk breast cancer

Researchers have found some women with early-stage, low-risk breast cancer may not need radiotherapy after breast conserving surgery.

from Breast Cancer News -- ScienceDaily https://ift.tt/MbeHZmX

Outdoor air pollution may increase non-lung cancer risk in older adults

Chronic exposure to fine particulate air pollutants (PM2.5) and nitrogen dioxide (NO2) may increase non-lung cancer risk in older adults, according to a new study. In a cohort study of millions of Medicare beneficiaries, the researchers found that exposures to PM2.5 and NO2 over a 10-year period increased the risk of developing colorectal and prostate cancers. The researchers also found that even low levels of air pollution exposure may make people particularly susceptible to developing these cancers, in addition to breast and endometrial cancers.

from Breast Cancer News -- ScienceDaily https://ift.tt/TNftwPG

Safety of AI-supported mammography screening

Mammography screening supported by artificial intelligence (AI) is a safe alternative to today's conventional double reading by radiologists and can reduce heavy workloads for doctors. This has now been shown in an interim analysis of a prospective, randomised controlled trial, which addressed the clinical safety of using AI in mammography screening.

from Breast Cancer News -- ScienceDaily https://ift.tt/yIru7PE