This new antibody may stop one of the deadliest breast cancers

Researchers have identified a promising new weapon against triple-negative breast cancer, one of the most aggressive forms of the disease. An experimental antibody targets a protein that fuels tumor growth and shuts down immune defenses, effectively turning the immune system back on. In early tests, the treatment slowed tumor growth, reduced lung metastases, and destroyed chemotherapy-resistant cancer cells.

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A common painkiller may be quietly changing cancer risk

Ibuprofen may be doing more than easing aches and pains—it could also help reduce the risk of some cancers. Studies have linked regular use to lower rates of endometrial and bowel cancer, likely because the drug dampens inflammation that fuels tumor growth. Researchers have even found it can interfere with genes cancer cells rely on to survive. Still, experts warn that long-term use carries risks and shouldn’t replace proven prevention strategies.

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A common painkiller may be quietly changing cancer risk

Ibuprofen may be doing more than easing aches and pains—it could also help reduce the risk of some cancers. Studies have linked regular use to lower rates of endometrial and bowel cancer, likely because the drug dampens inflammation that fuels tumor growth. Researchers have even found it can interfere with genes cancer cells rely on to survive. Still, experts warn that long-term use carries risks and shouldn’t replace proven prevention strategies.

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How cancer disrupts the brain and triggers anxiety and insomnia

Scientists have discovered that breast cancer can quietly throw the brain’s internal clock off balance—almost immediately after cancer begins. In mice, tumors flattened the natural daily rhythm of stress hormones, disrupting the brain-body feedback loop that regulates stress, sleep, and immunity. Remarkably, when researchers restored the correct day-night rhythm in specific brain neurons, stress hormone cycles snapped back into place, immune cells flooded the tumors, and the cancers shrank—without using any anti-cancer drugs.

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Vitamin A may be helping cancer hide from the immune system

A vitamin A byproduct has been found to quietly disarm the immune system, allowing tumors to evade attack and weakening cancer vaccines. Scientists have now developed a drug that shuts down this pathway, dramatically boosting immune responses and slowing cancer growth in preclinical studies.

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Northwestern Medicine’s new antibody wakes the immune system against pancreatic cancer

Pancreatic cancer uses a sugar-coated disguise to evade the immune system, helping explain why it’s so hard to treat. Northwestern scientists discovered this hidden mechanism and created an antibody that strips away the tumor’s protective signal. In animal tests, immune cells sprang back into action and tumors grew much more slowly. The team is now refining the therapy for future human trials.

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Scientists discover how the uterus knows when to push during childbirth

Childbirth depends not just on hormones, but on the uterus’s ability to sense physical force. Scientists found that pressure and stretch sensors in uterine muscles and surrounding nerves work together to trigger coordinated contractions. When these sensors are disrupted, contractions weaken and delivery slows. The discovery helps explain stalled labor—and could one day lead to better ways to manage childbirth.

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Long COVID may be fueled by inflammation and tiny clots

Long COVID affects an estimated 65 million people worldwide and can damage the brain, heart, blood vessels, and immune system long after infection. Researchers now link symptoms to lingering virus, inflammation, micro-clots, and disrupted energy metabolism. While structured rehab and pacing can improve quality of life, a growing list of experimental treatments—from antivirals and metformin to microbiome therapies and biologics—shows early promise. Clear answers, however, are still limited by small studies and the lack of large, definitive trials.

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A global cancer surge is underway and the world is not ready

Global cancer cases have surged dramatically, doubling since 1990 and reaching 18.5 million new diagnoses in 2023. Deaths have also climbed to over 10 million a year, with the steepest increases hitting low- and middle-income countries. Without urgent action, researchers project more than 30 million new cases annually by 2050. Alarmingly, around four in ten cancer deaths are tied to preventable risks such as smoking, poor diet, and high blood sugar.

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A smarter way to screen for breast cancer is emerging

A groundbreaking study shows that breast cancer screening works better when it’s personalized. Instead of annual mammograms for all, women were screened based on genetics, health history, and lifestyle factors. This approach reduced advanced cancers without increasing risk for those screened less often. Most women preferred the personalized model, hinting at a major shift in future screening guidelines.

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